2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole

Base Information

Chemical Name:2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole
CAS No.:60857-32-1
Molecular Formula:C12H11Cl4N
Molecular Weight:311.038
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00515109
Nikkaji Number:J145.518D
Wikidata:Q82375841
Mol file:60857-32-1.mol

Synonyms:60857-32-1;2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole;DTXSID00515109

Suppliers and Price of 2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole

Chemical Property:

PSA：4.93000
LogP:6.00990
XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:1
Exact Mass:310.961610
Heavy Atom Count:17
Complexity:269

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)N1C=C2C(=C1)C(=C(C(=C2Cl)Cl)Cl)Cl

Technology Process of 2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole

There total 6 articles about 2-tert-Butyl-4,5,6,7-tetrachloro-2H-isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 877-08-7
1,2,3,4-tetrachloro-5,6-dimethyl-benzene

: 60857-32-1
2-tert-Butyl-4,5,6,7-tetrachlor-2H-isoindol

Guidance literature:: Multi-step reaction with 4 steps

1: N-bromosuccinimide, azobisisobutyronitrile / CCl₄ / 2.5 h / Heating; Irradiation

2: 77 percent / benzyltrimethylammonium chloride / CHCl₃; ethanol; H₂O / 1 h / Heating

3: 90 percent / aq. H₂O₂, HCOOH / methanol / 4 h / Ambient temperature

4: NEt₃, Ac₂O / CHCl₃ / 1 h / Ambient temperature

With N-Bromosuccinimide; formic acid; 2,2'-azobis(isobutyronitrile); dihydrogen peroxide; acetic anhydride; benzyltrimethylammonium chloride; triethylamine; In methanol; tetrachloromethane; ethanol; chloroform; water;

Reference yield:

: 126134-12-1
2-tert-Butyl-4,5,6,7-tetrachlorisoindolin-N-oxid

: 60857-32-1
2-tert-Butyl-4,5,6,7-tetrachlor-2H-isoindol

Guidance literature:: With acetic anhydride; triethylamine; In chloroform; for 1h; Yield given; Ambient temperature;

Reference yield:

: 95-47-6
o-xylene

: 60857-32-1
2-tert-Butyl-4,5,6,7-tetrachlor-2H-isoindol

Guidance literature:: Multi-step reaction with 5 steps

1: 65 percent / SO₂Cl₂, S₂Cl₂, AlCl₃ / 1) 5 h, rt, 2) 1 h, 100 deg C, 3) 18 h, rt

2: N-bromosuccinimide, azobisisobutyronitrile / CCl₄ / 2.5 h / Heating; Irradiation

3: 77 percent / benzyltrimethylammonium chloride / CHCl₃; ethanol; H₂O / 1 h / Heating

4: 90 percent / aq. H₂O₂, HCOOH / methanol / 4 h / Ambient temperature

5: NEt₃, Ac₂O / CHCl₃ / 1 h / Ambient temperature

With disulfur dichloride; N-Bromosuccinimide; aluminium trichloride; formic acid; sulfuryl dichloride; 2,2'-azobis(isobutyronitrile); dihydrogen peroxide; acetic anhydride; benzyltrimethylammonium chloride; triethylamine; In methanol; tetrachloromethane; ethanol; chloroform; water;