877-08-7

Basic information

• Product Name: 1,2,3,4-Tetrachloro-5,6-Dimethylbenzylene
• Synonyms: 1,2,3,4-Tetrachloro-5,6-Dimethylbenzylene;tretrachloro-o-xylene;1,2,3,4-Tetrachloro-5,6-dimethylbenzene.;Benzene, 1,2,3,4-tetrachloro-5,6-dimethyl-;Tetrachloro-o-xylene, [solid]
• CAS NO: 877-08-7
• Molecular Formula: C₈H₆Cl₄
• Molecular Weight: 243.94524
• Mol File: 877-08-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 228°C
• Boiling Point: 272.29°C (estimate)
• Flash Point: 146.4°C
• Appearance: /
• Density: 1.6545 (estimate)
• Vapor Pressure: 0.00106mmHg at 25°C
• Refractive Index: 1.5149 (estimate)
• CAS DataBase Reference: 1,2,3,4-Tetrachloro-5,6-Dimethylbenzylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4-Tetrachloro-5,6-Dimethylbenzylene(877-08-7)
• EPA Substance Registry System: 1,2,3,4-Tetrachloro-5,6-Dimethylbenzylene(877-08-7)

Safety Data

• Hazardous Substances Data: 877-08-7(Hazardous Substances Data)

Usage

General Description

A powdered or flaked solid. Insoluble in water. Very strongly irritates skin, eyes or mucous membranes. May be toxic by ingestion.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Simple aromatic halogenated organic compounds, such as TETRACHLORO-O-XYLENE, are very unreactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Materials in this group may be incompatible with strong oxidizing and reducing agents. Also, they may be incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

InChI:InChI=1/C8H6Cl4/c1-3-4(2)6(10)8(12)7(11)5(3)9/h1-2H3

Upstream product

• 52331-02-9 1,4-dichloro-2,3-dimethyl-benzene 
• 24365-29-5 Tetrachlor-o-Dewar-xylol 
• 51238-67-6 1,3-dichloro-5,5-dimethyl-cyclohexa-1,3-diene 
• 95-47-6 o-xylene 
• 7553-56-2 iodine 
• 854857-45-7 2,3-dichloro-5,6-dimethyl-aniline 
• 52827-70-0 4-Chlor-2,3-dimethylanilin 
• 24365-28-4 C₁₂H₁₂Cl₄O₃ 
• 7298-89-7 2-chloro-5,5-dimethyl-1,3-cyclohexanedione 

Downstream Products

• 55776-53-9 2,3,6-Trichloro-4-hydroxy-4,5-dimethyl-cyclohexa-2,5-dienone 
• 56985-62-7 2,3,6-Trichloro-4,5-dimethyl-4-nitro-cyclohexa-2,5-dienone 
• 55980-47-7 2,3,6-Trichloro-4,5-dimethyl-4-nitrooxy-cyclohexa-2,5-dienone 
• 25641-94-5 1,2,3,4-tetrachloro-5,6-bis-dichloromethyl-benzene 
• 1402159-55-0 C₄₅H₄₅NO₉ 
• 1402159-52-7 C₁₇H₁₇Cl₄NO₅ 
• 1402159-49-2 ethyl 2-acetamido-4,5,6,7-tetrachloro-2,3-dihydroindene-2-carboxylate 
• 1402159-47-0 ethyl 4,5,6,7-tetrachloro-2-isocyano-2,3-dihydroindene-2-carboxylate 
• 1402159-69-6 C₁₄H₄Cl₄N₄ 
• 1402159-67-4 methyl 2-acetamido-5,6,7,8-tetrachloro-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 1402159-64-1 dimethyl 5,6,7,8-tetrachloro-1,4-dihydronaphthalene-2,3-dicarboxylate 
• 1402159-63-0 C₈H₄Cl₄O₂S 
• 1018-96-8 1-Methyl-2-acetoxymethyl-3,4,5,6-tetrachlor-benzol 
• 99861-04-8 1-Propyloxymethyl-2-methyl-3,4,5,6-tetrachlor-benzol 

Relevant articles and documents

Diversity oriented approach to polycyclic compounds through the diels-alder reaction and the Suzuki coupling

A diversity oriented strategy has been demonstrated to deliver small "drug like" molecules using alkylation, Diels-Alder reaction, and Suzuki-Miyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.

Studies on the Chemistry of Isoindoles and Isoindolenines, XXXI. 4,5,6,7-Tetrachloro-and 4,5,6,7-Tetrabromo-2H-isoindoles

The crystalline 2H-isoindoles 4b are synthesized starting with substituted 2-methylsulfonyl-2,3-dihydro-1H-isoindoles 3 by base-induced elimination of methanesulfinic acid.Compared with the parent compound, a considerable thermal stabilization and chemical deactivation is caused by the halogen atoms at the carbocyclic system.The spectroscopic properties of the o-quinonoid hetarenes 4b have been investigated.