N-Hydroxy-2,4,6-trimethylbenzamide

Base Information

Chemical Name:N-Hydroxy-2,4,6-trimethylbenzamide
CAS No.:6095-73-4
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID50540623
Wikidata:Q82416681

Synonyms:N-Hydroxy-2,4,6-trimethylbenzamide;6095-73-4;mesitohydroximic acid;SCHEMBL5800687;DTXSID50540623;AKOS000188231

Suppliers and Price of N-Hydroxy-2,4,6-trimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-Hydroxy-2,4,6-trimethylbenzamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:181

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)C)C(=O)NO)C

Technology Process of N-Hydroxy-2,4,6-trimethylbenzamide

There total 2 articles about N-Hydroxy-2,4,6-trimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 938-18-1
mesitylene-2-carboxylic acid chloride

: 6095-73-4
2,4,6-trimethylbenzohydroxamic acid

Guidance literature:: With hydroxylamine hydrochloride; potassium carbonate; In water; ethyl acetate; at 0 - 20 ℃; for 16h;
DOI:10.1039/c8ob00490k

Reference yield:

: 480-63-7
mesitylenecarboxylic acid

: 6095-73-4
2,4,6-trimethylbenzohydroxamic acid

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 60 °C

2: potassium carbonate; hydroxylamine hydrochloride / water; ethyl acetate / 0 - 25 °C

With thionyl chloride; hydroxylamine hydrochloride; potassium carbonate; N,N-dimethyl-formamide; In dichloromethane; water; ethyl acetate;
DOI:10.1021/acs.orglett.0c01183

Reference yield: 86.0%

: 6095-73-4
2,4,6-trimethylbenzohydroxamic acid

: 171258-08-5
2-(phenylethynyl)acetophenone

: N-mesityl-3-phenylnaphthalen-1-amine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium acetate; In toluene; at 100 ℃; for 8h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.0c01183