METHYL 4-(P-NITROPHENOXY)BUTYRATE

Base Information

• Chemical Name: METHYL 4-(P-NITROPHENOXY)BUTYRATE
• CAS No.: 28341-53-9
• Molecular Formula: C11H13 N O5
• Molecular Weight: 239.22
• Hs Code.: 2918990090
• Mol file: 28341-53-9.mol

Synonyms:Butyricacid, 4-(p-nitrophenoxy)-, methyl ester (8CI); Methyl4-(4-nitrophenoxy)-butyrate

Chemical Property of METHYL 4-(P-NITROPHENOXY)BUTYRATE

Chemical Property:

• Vapor Pressure: 6.93E-06mmHg at 25°C
• Boiling Point: 377.1°C at 760 mmHg
• Flash Point: 168.3°C
• PSA: 81.35000
• Density: 1.228g/cm³
• LogP: 2.45000

Purity/Quality:

99.0%Min ^*data from raw suppliers

Methyl 4-(p-nitrophenoxy)butyrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of METHYL 4-(P-NITROPHENOXY)BUTYRATE

There total 2 articles about METHYL 4-(P-NITROPHENOXY)BUTYRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Methyl 4-bromobutyrate (4897-84-1) → methyl 4-(4-nitrophenoxy)butyrate (28341-53-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 16h;

DOI:10.1016/j.bmc.2013.09.023

Reference yield:

→ methyl 4-(4-nitrophenoxy)butyrate (28341-53-9)

Guidance literature:

aus p-Nitro-phenol, 4-Chlor-buttersaeure-methylester;

Reference yield:

methyl 4-(4-nitrophenoxy)butyrate (28341-53-9) → 4-(4-nitrophenoxy)butanoic acid (28341-54-0)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; for 2h; Reflux;

DOI:10.1016/j.bmc.2013.09.023

upstream raw materials:

4-nitro-phenol

Methyl 4-bromobutyrate

Downstream raw materials:

4-(4-Amino-phenoxy)-butyric acid methyl ester

4-{4-[bis-(2-chloro-ethyl)-amino]-phenoxy}-butyric acid

4-{4-[bis-(2-hydroxy-ethyl)-amino]-phenoxy}-butyric acid methyl ester

4-{4-[bis-(2-chloro-ethyl)-amino]-phenoxy}-butyric acid methyl ester

Refernces