(R)-2-(N-Phenyl-aminooxy)-butan-1-ol

Base Information

Chemical Name:(R)-2-(N-Phenyl-aminooxy)-butan-1-ol
CAS No.:612808-36-3
Molecular Formula:C10H15NO2
Molecular Weight:181.235
Hs Code.:
DSSTox Substance ID:DTXSID90473481
Nikkaji Number:J2.090.913G
Wikidata:Q82302906

Synonyms:(R)-2-(N-Phenyl-aminooxy)-butan-1-ol;612808-36-3;SCHEMBL2436746;DTXSID90473481;ROCBZGZOXFTOLB-SNVBAGLBSA-N

Suppliers and Price of (R)-2-(N-Phenyl-aminooxy)-butan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (R)-2-(N-Phenyl-aminooxy)-butan-1-ol

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:124

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(CO)ONC1=CC=CC=C1
Isomeric SMILES:CC[C@H](CO)ONC1=CC=CC=C1

Technology Process of (R)-2-(N-Phenyl-aminooxy)-butan-1-ol

There total 6 articles about (R)-2-(N-Phenyl-aminooxy)-butan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 123-72-8
butyraldehyde

: 586-96-9
Nitrosobenzene

: 612808-36-3
(2R)-2-(N-phenylaminooxy)butan-1-ol

Guidance literature:: butyraldehyde; Nitrosobenzene; With C₂₅H₃₉NO₅; at 20 ℃; for 0.0666667h; pH=9.1; aq. phosphate buffer;

With sodium tetrahydroborate; In ethanol; at 0 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1007/s10562-011-0574-6

Reference yield:

: 771476-35-8
(2R)-2-(N-anilinyloxy)butanal

: 612808-36-3
(2R)-2-(N-phenylaminooxy)butan-1-ol

Guidance literature:: With sodium tetrahydroborate; In methanol; acetonitrile; at -20 ℃; for 0.166667h;
DOI:10.1016/j.tetlet.2003.09.057

Reference yield:

: 586-96-9
Nitrosobenzene

: 612808-36-3
(2R)-2-(N-phenylaminooxy)butan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: L-proline / acetonitrile / 24 h / -20 °C

2: NaBH₄ / propan-2-ol / 0.17 h / 20 °C

With sodium tetrahydroborate; L-proline; In isopropyl alcohol; acetonitrile;
DOI:10.1021/jo049338s