1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-

Base Information

Chemical Name:1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-
CAS No.:614726-85-1
Molecular Formula:C17H12Cl3N3O
Molecular Weight:380.661
Hs Code.:

Synonyms:5-(4-Chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-methyl-1H-pyrazole-3-carboxylic acid amide;5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide;AM4113;5-(4-chlorophenyl)-1-(2,4-dichloroohenyl)-4-methyl-1H-pyrazole-3-carboxylic acid amide;

Suppliers and Price of 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
AM4113
250mg
$ 125.00

Tocris
AM4113 ≥98%(HPLC)
50
$ 558.00

Tocris
AM4113 ≥98%(HPLC)
10
$ 133.00

ChemScene
CB1antagonist2 99.84%
5mg
$ 75.00

ChemScene
CB1antagonist2 99.84%
10mg
$ 125.00

ChemScene
CB1antagonist2 99.84%
100mg
$ 800.00

ChemScene
CB1antagonist2 99.84%
50mg
$ 450.00

Cayman Chemical
AM4113 ≥98%
25mg
$ 438.00

Cayman Chemical
AM4113 ≥98%
5mg
$ 113.00

Cayman Chemical
AM4113 ≥98%
1mg
$ 25.00

Total 14 raw suppliers

Chemical Property of 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-

Chemical Property:

Melting Point:185 - 186 °C
PSA：60.91000
LogP:5.60710

Purity/Quality:

97% ^*data from raw suppliers

AM4113 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses AM4113 is a novel cannabinoid CB1 receptor neutral antagonist and reverses the effects of the CB1 agonist AM411. CB1 antagonists like AM4113 are used in the development of treatment for diseases associated with neuronal dendritic abnormalities

Technology Process of 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-

There total 6 articles about 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 168273-05-0
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbonyl chloride

: 614726-85-1
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Guidance literature:: With ammonium hydroxide; In dichloromethane; water; at 0 - 20 ℃; for 0.5h;
DOI:10.1021/acschemneuro.1c00086

Reference yield: 90.0%

: 162758-35-2
rimonabant acid

: 614726-85-1
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Guidance literature:: rimonabant acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 0.666667h;

With ammonia; In dichloromethane; water; at 20 ℃;
DOI:10.1039/b807648k