1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Base Information

Chemical Name:1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid
CAS No.:618070-34-1
Molecular Formula:C11H9ClFNO3
Molecular Weight:257.649
Hs Code.:2933790090
European Community (EC) Number:632-208-8
Nikkaji Number:J2.138.088A
Mol file:618070-34-1.mol

Synonyms:1-(3-chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid;618070-34-1;SCHEMBL2289335;AKOS009265712;1-(3-CHLORO-4-FLUOROPHENYL)-2-OXO-3-PYRROLIDINECARBOXYLIC ACID

Suppliers and Price of 1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Heterocyclics
1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97%
5g
$ 750.00

Heterocyclics
1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97%
1g
$ 275.00

American Custom Chemicals Corporation
1-(3-CHLORO-4-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
10G
$ 7882.88

American Custom Chemicals Corporation
1-(3-CHLORO-4-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
5G
$ 4244.63

American Custom Chemicals Corporation
1-(3-CHLORO-4-FLUOROPHENYL)-2-OXOPYRROLIDINE-3-CARBOXYLIC ACID 95.00%
1G
$ 1030.84

Total 5 raw suppliers

Chemical Property of 1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

Chemical Property:

PSA：57.61000
LogP:1.98160
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:257.0254990
Heavy Atom Count:17
Complexity:339

Purity/Quality:

99% ^*data from raw suppliers

1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(=O)C1C(=O)O)C2=CC(=C(C=C2)F)Cl

Technology Process of 1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid

There total 1 articles about 1-(3-Chloro-4-fluorophenyl)-2-oxopyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 5617-70-9
cycl-isopropylidene cyclopropane-1,1-dicarboxylate

: 367-21-5
3-chloro-4-fluorophenylamine

: 618070-34-1
N-(3-chloro-4-fluorophenyl)-2-oxo-pyrrolidine-3-carboxylic acid

Guidance literature:: at 25 ℃;
DOI:10.1016/j.tet.2007.01.058

Reference yield: 78.0%

: 618070-34-1
N-(3-chloro-4-fluorophenyl)-2-oxo-pyrrolidine-3-carboxylic acid

: 848317-71-5
[N-(3-chloro-4-fluorophenyl)pyrrolidin-3-yl]methanol

Guidance literature:: With sodium tetrahydroborate; iodine; In tetrahydrofuran; at 25 ℃; for 2h;
DOI:10.1016/j.tetlet.2004.12.107

Reference yield:

: ethyl 7-((4-(4-aminophenoxy)-6-methoxyquinolin-7-yl)oxy)heptanoate

: 618070-34-1
N-(3-chloro-4-fluorophenyl)-2-oxo-pyrrolidine-3-carboxylic acid

: C₃₆H₃₇ClFN₃O₇

Guidance literature:: With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 40 ℃;
DOI:10.1016/j.bioorg.2020.103970