5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)-

Base Information

Chemical Name:5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)-
CAS No.:6216-67-7
Molecular Formula:C₂₄H₃₃N₆O₉P
Molecular Weight:580.535
Hs Code.:

Synonyms:((S)-1-{[(2R,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphoryloxymethyl}-3-methyl-butyl)-carbamic acid benzyl ester;

Suppliers and Price of 5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)-

Chemical Property:

Melting Point:149 °C
PSA：223.21000
LogP:2.47450

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of 5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)-

There total 11 articles about 5'-Adenylic acid, mono[4-methyl-2-[[(phenylmethoxy)carbonyl]amino]pentyl] ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1054645-97-4
Phenoxy-acetic acid (2R,3R,4R,5R)-5-[((S)-2-benzyloxycarbonylamino-4-methyl-pentyloxy)-hydroxy-phosphoryloxymethyl]-4-(2-phenoxy-acetoxy)-2-[6-(2-phenoxy-acetylamino)-purin-9-yl]-tetrahydro-furan-3-yl ester

: 6216-67-7
Adenosin-5'-phosphorsaeure-(N-benzyloxycarbonyl-L-leucinolat)

Guidance literature:: With ammonium hydroxide; at 5 ℃; for 0.5h;
DOI:10.1080/07328319808004322

Reference yield:

: 57018-82-3,81352-25-2
5'-O-dimethoxytrityladenosine

: 6216-67-7
Adenosin-5'-phosphorsaeure-(N-benzyloxycarbonyl-L-leucinolat)

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / 4.5 h / 0 °C

2: 48 percent / benzenesulphonic acid / CH₂Cl₂; methanol / 0.33 h

3: 0.17 h / Ambient temperature

4: 2.) H₂O / 1.) dioxane, 90 min, rt, 2.) 12 h, rt

5: aq. NH₃ / 0.5 h / 5 °C

With ammonium hydroxide; water; benzenesulfonic acid; In pyridine; methanol; dichloromethane;
DOI:10.1080/07328319808004322

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 6216-67-7
Adenosin-5'-phosphorsaeure-(N-benzyloxycarbonyl-L-leucinolat)

Guidance literature:: Multi-step reaction with 4 steps

1: diethyl ether / 1 h / Ambient temperature

2: 82 percent / H₂O / 2 h

3: 2.) H₂O / 1.) dioxane, 90 min, rt, 2.) 12 h, rt

4: aq. NH₃ / 0.5 h / 5 °C

With ammonium hydroxide; water; In diethyl ether; water;
DOI:10.1080/07328319808004322