CYCLOPENTYL-(1-PHENYL-ETHYL)-AMINE

Base Information

• Chemical Name: CYCLOPENTYL-(1-PHENYL-ETHYL)-AMINE
• CAS No.: 626213-92-1
• Molecular Formula: C13H19N
• Molecular Weight: 189.301
• Hs Code.: 2921499090
• Mol file: 626213-92-1.mol

Synonyms:Fendilin;Difmecor;3-diphenyl-propylamine;fendiline;

Chemical Property of CYCLOPENTYL-(1-PHENYL-ETHYL)-AMINE

Chemical Property:

• Boiling Point: 276.5±9.0 °C(Predicted)
• PKA: 9.95±0.20(Predicted)
• PSA: 12.03000
• Density: 0.96±0.1 g/cm3(Predicted)
• LogP: 3.67070

Purity/Quality:

98%min ^*data from raw suppliers

N-(1-phenylethyl)cyclopentanamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOPENTYL-(1-PHENYL-ETHYL)-AMINE

There total 6 articles about CYCLOPENTYL-(1-PHENYL-ETHYL)-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C13H17N → N-(1-phenylethyl)cyclopentanamine (626213-92-1)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 19h;

DOI:10.1039/c9cc02900a

Reference yield: 75.0%

Cyclopentamine (1003-03-8) + 2-(2-methoxyphenoxy)-1-phenylethan-1-ol → N-(1-phenylethyl)cyclopentanamine (626213-92-1) + 2-methoxy-phenol (90-05-1)

Guidance literature:

With palladium 10% on activated carbon; sodium formate; In toluene; at 150 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.cclet.2021.08.125

Reference yield:

N-(1-phenylethylidene)cyclopentylamine → N-(1-phenylethyl)cyclopentanamine (626213-92-1)

Guidance literature:

With potassium tert-butylate; hydrogen; RuHCl(R-BINAP)(R,R-CYDN); In benzene; for 36h; under 37503.8 Torr; Product distribution / selectivity;

upstream raw materials:

Cyclopentamine

2-(2-methoxyphenoxy)-acetophenone

α-bromoacetophenone

Refernces

• 1、 Mercea, Dan M.,Howlett, Michael G.,Piascik, Adam D.,Scott, Daniel J.,Steven, Alan,Ashley, Andrew E.,Fuchter, Matthew J.. "Enantioselective reduction of: N -alkyl ketimines with frustrated Lewis pair catalysis using chiral borenium ions". supporting information. p. 7077 - 7080. Retrieved 2019/06/20.