8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL

Base Information

Chemical Name:8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL
CAS No.:62835-68-1
Molecular Formula:C₁₉H₂₂ClN₃OS
Molecular Weight:375.922
Hs Code.:
DSSTox Substance ID:DTXSID20490868
Wikidata:Q82334910

Synonyms:62835-68-1;DTXSID20490868;8-CHLORO-10-[3-(PIPERAZIN-1-YL)PROPYL]-10H-PHENOTHIAZIN-3-OL

Suppliers and Price of 8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:375.1172112
Heavy Atom Count:25
Complexity:437

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1)CCCN2C3=C(C=C(C=C3)O)SC4=C2C=C(C=C4)Cl

Technology Process of 8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL

There total 2 articles about 8-Chloro-10-[3-(piperazin-1-YL)propyl]-10H-phenothiazin-3-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2002-32-6
8-chloro-10H-phenothiazin-3-ol

: 62835-68-1
7-Hydroxydesmethylprochlorperazin

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide

2: (i) NaH, DMSO, (ii) /BRN= 605278/, (iii) /BRN= 102555/, KI, butanone, (iv) HCl, MeOH

With potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570140121

Reference yield:

: 110-85-0
piperazine

: 62835-54-5
2-chloro-7-methoxymethoxy-10H-phenothiazine

: 109-70-6
1.3-chlorobromopropane

: 62835-68-1
7-Hydroxydesmethylprochlorperazin

Guidance literature:: Multistep reaction; (i) NaH, DMSO, (ii) /BRN= 605278/, (iii) /BRN= 102555/, KI, butanone, (iv) HCl, MeOH;
DOI:10.1002/jhet.5570140121