(2-Phenylphenyl)urea

Base Information

• Chemical Name: (2-Phenylphenyl)urea
• CAS No.: 13262-46-9
• Molecular Formula: C13H12N2O
• Molecular Weight: 212.251
• NSC Number: 190737
• DSSTox Substance ID: DTXSID10307330
• Wikidata: Q82054702
• ChEMBL ID: CHEMBL65026
• Mol file: 13262-46-9.mol

Synonyms:(2-phenylphenyl)urea;13262-46-9;NSC190737;CHEMBL65026;SCHEMBL4082544;{[1,1'-biphenyl]-2-yl}urea;DTXSID10307330;AKOS000154083;NSC-190737;CS-0249188;EN300-42715;Z285221644;2-Thiopheneacetic acid, .alpha.-hydroxy-.alpha.-2-thienyl-, (1.alpha.,2.beta.,4.beta.,5.alpha.,7.beta.)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester

Chemical Property of (2-Phenylphenyl)urea

Chemical Property:

• Vapor Pressure: 1.09E-05mmHg at 25°C
• Boiling Point: 370.7°Cat760mmHg
• Flash Point: 178°C
• Density: 1.213g/cm³
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 212.094963011
• Heavy Atom Count: 16
• Complexity: 236

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC=C2NC(=O)N

Technology Process of (2-Phenylphenyl)urea

There total 6 articles about (2-Phenylphenyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenyl carbamate (64-10-8) + benzenediazonium tetrafluoroborate (369-57-3) → 1-([1,1’-biphenyl]-2-yl)urea (13262-46-9)

Guidance literature:

With tris(bipyridine)ruthenium(II) dichloride hexahydrate; palladium diacetate; In methanol; at 20 ℃; for 19h; Reagent/catalyst; Solvent; chemoselective reaction; Sealed tube; Irradiation;

DOI:10.1039/d0cc01443e

Reference yield:

aniline (62-53-3) → 1-([1,1’-biphenyl]-2-yl)urea (13262-46-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: water; ethanol / 0.08 h / 20 °C

1.2: 2 h / 0 °C / Inert atmosphere

2.1: palladium diacetate; tris(bipyridine)ruthenium(II) dichloride hexahydrate / methanol / 19 h / 20 °C / Sealed tube; Irradiation

With tris(bipyridine)ruthenium(II) dichloride hexahydrate; palladium diacetate; In methanol; ethanol; water;

DOI:10.1039/d0cc01443e

Reference yield:

[1,1'-biphenyl]-2-yl-isocyanate (17337-13-2) → 1-([1,1’-biphenyl]-2-yl)urea (13262-46-9)

Guidance literature:

With ammonia; water;

DOI:10.1039/jr9320002225

upstream raw materials:

[1,1'-biphenyl]-2-yl-isocyanate

2-phenylaniline

phenyl carbamate

benzenediazonium tetrafluoroborate

Downstream raw materials:

9H-carbazole

1,3-di(biphenyl-2-yl)urea