2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid

Base Information

Chemical Name:2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid
CAS No.:63050-12-4
Molecular Formula:C₁₅H₁₃NO₅
Molecular Weight:287.272
Hs Code.:
DSSTox Substance ID:DTXSID001179181

Synonyms:SCHEMBL11283952;DTXSID001179181;2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid;63050-12-4

Suppliers and Price of 2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:287.07937252
Heavy Atom Count:21
Complexity:365

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=C(N=C1)COC2=CC=C(C=C2)CC(=O)O)C(=O)O

Technology Process of 2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid

There total 4 articles about 2-[[4-(Carboxymethyl)phenoxy]methyl]-3-pyridinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-(4-Carboxymethyl-phenoxymethyl)-nicotinic acid ethyl ester

: 63050-12-4
2-<4-(carboxymethyl)phenoxymethyl>pyridine-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; water; for 1h; Yield given; Heating;
DOI:10.1248/cpb.29.3515

Reference yield:

: 156-38-7
4-hydroxyphenylacetate

: 63050-12-4
2-<4-(carboxymethyl)phenoxymethyl>pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na / 1.) EtOH, 2.) EtOH, 2 h, reflux

2: KOH / ethanol; H₂O / 1 h / Heating

With potassium hydroxide; sodium; In ethanol; water;
DOI:10.1248/cpb.29.3515

Reference yield:

: 63050-11-3
ethyl 2-bromomethylpyridine-3-carboxylate

: 63050-12-4
2-<4-(carboxymethyl)phenoxymethyl>pyridine-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Na / 1.) EtOH, 2.) EtOH, 2 h, reflux

2: KOH / ethanol; H₂O / 1 h / Heating

With potassium hydroxide; sodium; In ethanol; water;
DOI:10.1248/cpb.29.3515