Benzenamine, N-ethyl-, hydrochloride

Base Information

• Chemical Name: Benzenamine, N-ethyl-, hydrochloride
• CAS No.: 4348-19-0
• Molecular Formula: C8H11 N . Cl H
• Molecular Weight: 157.643
• DSSTox Substance ID: DTXSID7063425
• Mol file: 4348-19-0.mol

Synonyms:N-ethylaniline hydrochloride;4348-19-0;Benzenamine, N-ethyl-, hydrochloride;Benzenamine, N-ethyl-, hydrochloride (1:1);Aniline, N-ethyl-, hydrochloride;N-ETHYLANILINEHYDROCHLORIDE;DTXSID7063425

Chemical Property of Benzenamine, N-ethyl-, hydrochloride

Chemical Property:

• Vapor Pressure: 0.304mmHg at 25°C
• Boiling Point: 201.7°Cat760mmHg
• Flash Point: 85°C
• PSA: 12.03000
• Density: g/cm³
• LogP: 2.99340
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 157.0658271
• Heavy Atom Count: 10
• Complexity: 65

Purity/Quality:

98% ^*data from raw suppliers

N-ETHYLANILINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNC1=CC=CC=C1.Cl

Technology Process of Benzenamine, N-ethyl-, hydrochloride

There total 6 articles about Benzenamine, N-ethyl-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N-methyl-N-ethylaniline (613-97-8) → N-ethylaniline hydrochloride (4348-19-0)

Guidance literature:

With aluminum oxide; silica gel; potassium carbonate; sodium percarbonate; sodium salt of 2,4-dichloro-6-hydroxy-1,3,5-triazine; In chloroform; column chromatography;

DOI:10.1021/ol036319g

Reference yield: 95.0%

Acetanilid (103-84-4) → N-ethylaniline hydrochloride (4348-19-0)

Guidance literature:

Acetanilid; With phenylsilane-d3; C₃₆H₄₈F₆N₆NiO₅S₂; In toluene; at 110 ℃; for 24h; Inert atmosphere; Schlenk technique;

With hydrogenchloride; In diethyl ether;

DOI:10.1039/d1cc03537a

Reference yield:

N-ethyl-N-phenylamine (103-69-5) → N-ethylaniline hydrochloride (4348-19-0)

Guidance literature:

With hydrogenchloride; In water;

DOI:10.1039/c5cp02294k

upstream raw materials:

aniline hydrochloride

N-methyl-N-ethylaniline

N-ethyl-N-phenylamine

acetaldehyde

Downstream raw materials:

1,2-dimethylindole

2-(ethyl(phenyl)amino)propanenitrile

N-ethyl-N-phenylammonium tricyanomethanide

N-ethyl-N-nitrosoaniline

Refernces

• 1、 Pandey, Pragati,Bera, Jitendra K.. "Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex". . p. 9204 - 9207. Retrieved 2021/09/20.
• 2、 Rosenau, Thomas,Hofinger, Andreas,Potthast, Antje,Kosma, Paul. "A General, Selective, High-Yield N-Demethylation Procedure for Tertiary Amines by Solid Reagents in a Convenient Column Chromatography-like Setup". . p. 541 - 544. Retrieved 2007/10/03.