Ethyl 2-acetamido-5-bromobenzoate

Base Information

• Chemical Name: Ethyl 2-acetamido-5-bromobenzoate
• CAS No.: 63243-78-7
• Molecular Formula: C11H12BrNO3
• Molecular Weight: 286.125
• European Community (EC) Number: 923-279-9
• DSSTox Substance ID: DTXSID401287425
• Mol file: 63243-78-7.mol

Synonyms:ethyl 2-acetamido-5-bromobenzoate;63243-78-7;DTXSID401287425;Ethyl 2-(acetylamino)-5-bromobenzoate

Chemical Property of Ethyl 2-acetamido-5-bromobenzoate

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 285.00006
• Heavy Atom Count: 16
• Complexity: 270

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCOC(=O)C1=C(C=CC(=C1)Br)NC(=O)C

Technology Process of Ethyl 2-acetamido-5-bromobenzoate

There total 2 articles about Ethyl 2-acetamido-5-bromobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

ethanol (64-17-5) + 1-acetyl-5-bromo-1H-indole-2,3-dione (81964-65-0) → ethyl 2-acetamido-5-bromobenzoate (63243-78-7)

Guidance literature:

With [bis(acetoxy)iodo]benzene; at 20 ℃; for 48h;

DOI:10.1055/s-0035-1560990

Reference yield:

→ ethyl 2-acetamido-5-bromobenzoate (63243-78-7)

Guidance literature:

Aethyl-5-bromanthranilat, Acetanhydrid;

DOI:10.1016/0040-4020(77)80129-4

upstream raw materials:

ethanol

1-acetyl-5-bromo-1H-indole-2,3-dione