Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-

Base Information

Chemical Name:Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-
CAS No.:145131-13-1
Molecular Formula:C₂₉H₃₉N₃O
Molecular Weight:445.648
Hs Code.:
DSSTox Substance ID:DTXSID30162887
Nikkaji Number:J759.424K
Wikidata:Q83031668
Mol file:145131-13-1.mol

Synonyms:N-(2,6-Bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)urea;Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-;N(sup 1)-(2,6-Diisopropylphenyl)-N(sup 2)-(2-(1-(1-methyl-3-indolyl)cyclopentyl)ethyl)urea;145131-13-1;C29H39N3O;DTXSID30162887;LS-159103;N-[2-[1-(1-Methyl-1H-indol-3-yl)cyclopentyl]ethyl]-N'-(2,6-diisopropylphenyl)urea

Suppliers and Price of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-

Chemical Property:

Vapor Pressure:4.83E-13mmHg at 25°C
Boiling Point:570.8°Cat760mmHg
Flash Point:299°C
Density:1.1g/cm³
XLogP3:7.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:7
Exact Mass:445.309312876
Heavy Atom Count:33
Complexity:625

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(C(=CC=C1)C(C)C)NC(=O)NCCC2(CCCC2)C3=CN(C4=CC=CC=C43)C

Technology Process of Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)-

There total 6 articles about Urea, N-(2,6-bis(1-methylethyl)phenyl)-N'-(2-(1-(1-methyl-1H-indol-3-yl)cyclopentyl)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 28178-42-9
2,6-diisopropylphenyl isocyanate

: 145132-35-0
2-[1-(1-Methyl-1H-indol-3-yl)-cyclopentyl]-ethylamine

: 145131-13-1
1-(2,6-Diisopropyl-phenyl)-3-{2-[1-(1-methyl-1H-indol-3-yl)-cyclopentyl]-ethyl}-urea

Guidance literature:: In di-isopropyl ether; Ambient temperature;
DOI:10.1016/0223-5234(96)80445-4

Reference yield:

: 771-51-7
indole-3-acetonitrile

: 145131-13-1
1-(2,6-Diisopropyl-phenyl)-3-{2-[1-(1-methyl-1H-indol-3-yl)-cyclopentyl]-ethyl}-urea

Guidance literature:: Multi-step reaction with 6 steps

1: 60 percent / triton B, aq. NaOH / methanol / 3 h / Ambient temperature

2: 62 percent / NaH / dimethylsulfoxide; diethyl ether / 4 h / Heating

3: 53 percent / diisobutylaluminum hydride / toluene / -60 - 20 °C

4: 1.) 2,4,6-triisopropylbenzenesulfonylhydrazide / 1.) THF, RT, 3 h, 2.) MeOH, reflux, 4.5 h

5: 74 percent / LiAlH₄ / Heating

6: 25 percent / diisopropyl ether / Ambient temperature

With sodium hydroxide; lithium aluminium tetrahydride; trisylhydrazine; N-benzyl-trimethylammonium hydroxide; sodium hydride; diisobutylaluminium hydride; In methanol; diethyl ether; di-isopropyl ether; dimethyl sulfoxide; toluene;
DOI:10.1016/0223-5234(96)80445-4

Reference yield:

: 51584-17-9
1-methyl-1H-indole-3-acetonitrile

: 145131-13-1
1-(2,6-Diisopropyl-phenyl)-3-{2-[1-(1-methyl-1H-indol-3-yl)-cyclopentyl]-ethyl}-urea

Guidance literature:: Multi-step reaction with 5 steps

1: 62 percent / NaH / dimethylsulfoxide; diethyl ether / 4 h / Heating

2: 53 percent / diisobutylaluminum hydride / toluene / -60 - 20 °C

3: 1.) 2,4,6-triisopropylbenzenesulfonylhydrazide / 1.) THF, RT, 3 h, 2.) MeOH, reflux, 4.5 h

4: 74 percent / LiAlH₄ / Heating

5: 25 percent / diisopropyl ether / Ambient temperature

With lithium aluminium tetrahydride; trisylhydrazine; sodium hydride; diisobutylaluminium hydride; In diethyl ether; di-isopropyl ether; dimethyl sulfoxide; toluene;
DOI:10.1016/0223-5234(96)80445-4