4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine

Base Information

Chemical Name:4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine
CAS No.:5020-62-2
Molecular Formula:C19H19ClF3N3O
Molecular Weight:397.8219
Hs Code.:
DSSTox Substance ID:DTXSID60412423
Wikidata:Q82219774

Synonyms:4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine;5020-62-2;DTXSID60412423

Suppliers and Price of 4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine

Chemical Property:

Vapor Pressure:1.18E-11mmHg at 25°C
Boiling Point:538.2°Cat760mmHg
Flash Point:279.3°C
Density:1.328g/cm³
XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:397.1168744
Heavy Atom Count:27
Complexity:482

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=N1)C2=C(C3=C(C=CC(=C3N2)C(F)(F)F)Cl)CCCCN

Technology Process of 4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine

There total 15 articles about 4-[4-chloro-2-(6-methoxypyridin-2-yl)-7-(trifluoromethyl)-1H-indol-3-yl]butan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 139190-29-7
(Indan-4-yl)acetonitrile

: 5020-62-2
(4-indanyl)acetic acid

Guidance literature:: With sodium hydroxide; for 6h; Heating;

Reference yield:

: 103989-64-6
2-(4-Indan-1-onyl)-essigsaeure

: 5020-62-2
(4-indanyl)acetic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In diethyl ether;
DOI:10.1021/ja01490a038

Reference yield:

: 70526-40-8
3-(2-carboxymethylphenyl)propionic acid

: 5020-62-2
(4-indanyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: polyphosphoric acid

2: H₂ / Pd-C / diethyl ether

With PPA; hydrogen; palladium on activated charcoal; In diethyl ether;
DOI:10.1021/ja01490a038