Cyclohexanone dimethylhydrazone

Base Information

• Chemical Name: Cyclohexanone dimethylhydrazone
• CAS No.: 10424-93-8
• Molecular Formula: C8H16 N2
• Molecular Weight: 140.228
• Hs Code.: 2928000090
• NSC Number: 126439
• UNII: X27D2T2EQK
• DSSTox Substance ID: DTXSID80298847
• Nikkaji Number: J121.638D
• Mol file: 10424-93-8.mol

Synonyms:Cyclohexanone dimethylhydrazone;10424-93-8;N-(cyclohexylideneamino)-N-methylmethanamine;Cyclohexanone, dimethylhydrazone;Cyclohexanone dimethyl hydrazone;Cyclohexanone N,N-dimethylhydrazone;NSC-126439;2-CYCLOHEXYLIDENE-1,1-DIMETHYLHYDRAZINE;X27D2T2EQK;SCHEMBL2579553;DTXSID80298847;NSC126439;AKOS015906216;N'-Cyclohexylidene-N,N-dimethyl-hydrazine;N,N-DIMETHYLCYCLOHEXANONE HYDRAZONE;2-(1-Cyclohexen-1-yl)-1,1-dimethylhydrazine;Hydrazine, 2-(1-cyclohexen-1-yl)-1,1-dimethyl-;124315-65-7

Chemical Property of Cyclohexanone dimethylhydrazone

Chemical Property:

• Vapor Pressure: 0.274mmHg at 25°C
• Boiling Point: 203.7°Cat760mmHg
• Flash Point: 77°C
• PSA: 15.60000
• Density: 0.95g/cm³
• LogP: 1.86810
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 140.131348519
• Heavy Atom Count: 10
• Complexity: 119

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)N=C1CCCCC1

Technology Process of Cyclohexanone dimethylhydrazone

There total 4 articles about Cyclohexanone dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + N,N-Dimethylhydrazine (57-14-7) → N'-cyclohexylidene-N,N-dimethyl-hydrazine (10424-93-8)

Guidance literature:

at 80 ℃; for 14h;

DOI:10.1039/P19920000083

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + Trimethylhydrazin (1741-01-1) → N'-cyclohexylidene-N,N-dimethyl-hydrazine (10424-93-8)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; Heating;

Reference yield:

→ N'-cyclohexylidene-N,N-dimethyl-hydrazine (10424-93-8) + ethyl α-phenylacetoacetate dimethyl hydrazone (57632-12-9)

Guidance literature:

upstream raw materials:

cyclohexanone

N,N-Dimethylhydrazine

Trimethylhydrazin

Downstream raw materials:

[2-(Dimethyl-hydrazono)-cyclohexyl]-diphenyl-methanol

syn-2-Methylcyclohexanondimethylhydrazon

N'-[2-[1,3]Dioxolan-2-ylmethyl-cyclohex-(E)-ylidene]-N,N-dimethyl-hydrazine

cyclohexanone

Refernces

• 1、 Karmakar, Rajdip,Rheingold, Arnold L.,Micalizio, Glenn C.. "Studies Targeting Ryanodol Result in an Annulation Reaction for the Synthesis of a Variety of Fused Carbocycles". . p. 6126 - 6129. Retrieved 2019.
• 2、 Beltran, Frédéric,Miesch, Laurence. "Tertiary Enamide-Triggered SEAr: Domino Allylation and Enamine-Type Addition". supporting information. p. 1569 - 1573. Retrieved 2019/03/12.
• 3、 Walters, Jennifer C.,Tierno, Anthony F.,Dubin, Aimee H.,Wengryniuk, Sarah E.. "(Poly)cationic λ3-Iodane-Mediated Oxidative Ring Expansion of Secondary Alcohols". supporting information. p. 1460 - 1464. Retrieved 2018/04/06.