Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]-

Base Information

Chemical Name:Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]-
CAS No.:633303-19-2
Molecular Formula:C43H43ClN12O9
Molecular Weight:907.342
Hs Code.:

Glycine,
N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl
methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid
azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1-
methyl-1H-imidazol-2-yl]carbonyl]-

Synonyms:

Suppliers and Price of Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]-

There total 12 articles about Glycine, N-[[4-[[[4-[[[4-[[4-[7-(acetylamino)-1-(chloromethyl)-1,2-dihydro-5-(phenyl methoxy)-3H-benz[e]indol-3-yl]-1,4-dioxobutyl]amino]-1-methyl-1H-imid azol-2-yl]carbonyl]amino]-1-methyl-1H-imidazol-2-yl]carbonyl]amino]-1- methyl-1H-imidazol-2-yl]carbonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 120095-64-9
2,2,2-trichloro-1-(1-methyl-4-nitro-1H-imidazol-2-yl)ethan-1-one

: 633303-19-2
[(4-{[4-({4-[4-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indol-3-yl)-4-oxobutyrylamino]-1-methyl-1H-imidazole-2-carbonyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-imidazole-2-carbonyl)amino]acetic acid

Guidance literature:: Multi-step reaction with 10 steps

1: 87 percent / Et₃N / tetrahydrofuran / 4 h / 20 °C

2: NaOH / tetrahydrofuran; methanol

3: 72 percent / H₂SO₄ / tetrahydrofuran / 36 h / 20 °C

4: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

5: 1.25 g / Et₃N / tetrahydrofuran / 2 h / 20 °C

6: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

7: 1 percent / Et₃N / tetrahydrofuran / 2 h / 20 °C

8: H₂ / Pd/C / methanol / 2 h / 20 °C / 2585.81 Torr

9: 1.2 g / HOBt; EDCI / dimethylformamide / 12 h / 20 °C

10: 63 percent / TiCl₄ / CH₂Cl₂ / 24 h / 20 °C

With sodium hydroxide; sulfuric acid; hydrogen; titanium tetrachloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b303650m

Reference yield:

: 633303-10-3
[(1-methyl-4-nitro-1H-imidazole-2-carbonyl)amino]acetic acid

: 633303-19-2
[(4-{[4-({4-[4-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indol-3-yl)-4-oxobutyrylamino]-1-methyl-1H-imidazole-2-carbonyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-imidazole-2-carbonyl)amino]acetic acid

Guidance literature:: Multi-step reaction with 8 steps

1: 72 percent / H₂SO₄ / tetrahydrofuran / 36 h / 20 °C

2: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

3: 1.25 g / Et₃N / tetrahydrofuran / 2 h / 20 °C

4: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

5: 1 percent / Et₃N / tetrahydrofuran / 2 h / 20 °C

6: H₂ / Pd/C / methanol / 2 h / 20 °C / 2585.81 Torr

7: 1.2 g / HOBt; EDCI / dimethylformamide / 12 h / 20 °C

8: 63 percent / TiCl₄ / CH₂Cl₂ / 24 h / 20 °C

With sulfuric acid; hydrogen; titanium tetrachloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b303650m

Reference yield:

: 633302-89-3
[(1-methyl-4-nitro-1H-imidazole-2-carbonyl)amino]acetic acid methyl ester

: 633303-19-2
[(4-{[4-({4-[4-(7-acetylamino-5-benzyloxy-1-chloromethyl-1,2-dihydrobenzo[e]indol-3-yl)-4-oxobutyrylamino]-1-methyl-1H-imidazole-2-carbonyl}amino)-1-methyl-1H-imidazole-2-carbonyl]amino}-1-methyl-1H-imidazole-2-carbonyl)amino]acetic acid

Guidance literature:: Multi-step reaction with 9 steps

1: NaOH / tetrahydrofuran; methanol

2: 72 percent / H₂SO₄ / tetrahydrofuran / 36 h / 20 °C

3: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

4: 1.25 g / Et₃N / tetrahydrofuran / 2 h / 20 °C

5: H₂ / Pd/C / methanol / 2 h / 2585.81 Torr

6: 1 percent / Et₃N / tetrahydrofuran / 2 h / 20 °C

7: H₂ / Pd/C / methanol / 2 h / 20 °C / 2585.81 Torr

8: 1.2 g / HOBt; EDCI / dimethylformamide / 12 h / 20 °C

9: 63 percent / TiCl₄ / CH₂Cl₂ / 24 h / 20 °C

With sodium hydroxide; sulfuric acid; hydrogen; titanium tetrachloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b303650m