2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine

Base Information

• Chemical Name: 2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine
• CAS No.: 83522-07-0
• Molecular Formula: C12H18N2O
• Molecular Weight: 0
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID101003509
• Nikkaji Number: J78.646B
• Mol file: 83522-07-0.mol

Synonyms:2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine;BRN 5523514;83522-07-0;Oxazolidine, 2-(p-(dimethylamino)phenyl)-3-methyl-;N,N-dimethyl-4-(3-methyl-1,3-oxazolidin-2-yl)aniline;2-[p-(Dimethylamino)phenyl]-3-methyloxazolidine;DTXSID101003509;AKOS003578549;LS-100277

Chemical Property of 2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine

Chemical Property:

• Vapor Pressure: 0.000628mmHg at 25°C
• Boiling Point: 309.7°C at 760 mmHg
• Flash Point: 91.7°C
• PSA: 15.71000
• Density: 1.068g/cm³
• LogP: 1.65110
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 206.141913202
• Heavy Atom Count: 15
• Complexity: 200

Purity/Quality:

99% ^*data from raw suppliers

2-(P-(DIMETHYLAMINO)PHENYL)-3-METHYLOXAZOLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCOC1C2=CC=C(C=C2)N(C)C

Technology Process of 2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine

There total 1 articles about 2-(p-(Dimethylamino)phenyl)-3-methyloxazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(2-hydroxyethyl)(methyl)amine (109-83-1) + 4-dimethylamino-benzaldehyde (100-10-7) → Dimethyl-[4-(3-methyl-oxazolidin-2-yl)-phenyl]-amine (83522-07-0)

Guidance literature:

Reference yield: 62.0%

1-bromo-hexane (111-25-1) + Dimethyl-[4-(3-methyl-oxazolidin-2-yl)-phenyl]-amine (83522-07-0) → 2-N-[1'-para-(N',N'-dimethylamino)phenylheptyl]-N-methylaminoethanol

Guidance literature:

Dimethyl-[4-(3-methyl-oxazolidin-2-yl)-phenyl]-amine; With naphthalene; lithium; In tetrahydrofuran; at -20 ℃; for 3.5h;

1-bromo-hexane; In tetrahydrofuran; at -20 ℃; for 0.166667h;

DOI:10.1016/S0040-4020(00)00303-3

Reference yield: 38.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + Dimethyl-[4-(3-methyl-oxazolidin-2-yl)-phenyl]-amine (83522-07-0) → 2-N-methyl-N-[α-(1'-hydroxycyclohexyl)-para-(N',N'-dimethylamino)-phenylheptyl]-methylaminoethanol

Guidance literature:

Dimethyl-[4-(3-methyl-oxazolidin-2-yl)-phenyl]-amine; With naphthalene; lithium; In tetrahydrofuran; at -20 ℃; for 3.5h;

cyclohexanone; In tetrahydrofuran; at -20 ℃; for 0.166667h;

DOI:10.1016/S0040-4020(00)00303-3

upstream raw materials:

(2-hydroxyethyl)(methyl)amine

4-dimethylamino-benzaldehyde

Downstream raw materials:

2-[(4-Dimethylamino-benzyl)-methyl-amino]-ethanol