1-(phenylthio)-2-aminopropane

Base Information

• Chemical Name: 1-(phenylthio)-2-aminopropane
• CAS No.: 2014-77-9
• Molecular Formula: C9H13 N S
• Molecular Weight: 167.275
• Hs Code.: 2930909090
• Mol file: 2014-77-9.mol

Synonyms:Ethylamine,1-methyl-2-(phenylthio)- (7CI,8CI); (R,S)-1-(Phenylthio)-2-aminopropane;1-(Phenylthio)-2-propanamine; 1-Methyl-2-phenylthioethylamine

Chemical Property of 1-(phenylthio)-2-aminopropane

Chemical Property:

• Vapor Pressure: 0.011mmHg at 25°C
• Boiling Point: 262.3°Cat760mmHg
• Flash Point: 112.4°C
• PSA: 51.32000
• Density: 1.05g/cm³
• LogP: 2.82620

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(phenylthio)-2-aminopropane

There total 6 articles about 1-(phenylthio)-2-aminopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

→ 1-methyl-2-(phenylsulfanyl)ethylamine (2014-77-9)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3.3h; Reflux;

Reference yield: 67.0%

thiophenol (108-98-5) + 2-Methylaziridine (75-55-8,41927-28-0,76612-76-5,76612-77-6,205537-16-2) → 1-methyl-2-(phenylsulfanyl)ethylamine (2014-77-9)

Guidance literature:

at 60 ℃; for 12h;

DOI:10.3987/com-07-11001

Reference yield:

thiophenol (108-98-5) → 1-methyl-2-(phenylsulfanyl)ethylamine (2014-77-9)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 134 - 202 °C

2: aq. HCl

With hydrogenchloride; In benzene;

DOI:10.1021/jo01045a025

upstream raw materials:

N-[1-methyl-2-(phenylthio)ethyl]acetamide

phenylmercaptopropanone oxime

thiophenol

2-Methylaziridine

Downstream raw materials:

7-Chloro-6-fluoro-1-(1-methyl-2-phenylsulfanyl-ethyl)-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid ethyl ester

1-Phenylthio-2-propyl-isocyanat

N-[(10-bromo-2,3,6-trimethoxyphenanthren-9-yl)methyl]-N-[1-methyl-2-(phenylsulfanyl)ethyl]amine

N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine