N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Base Information

Chemical Name:N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine
CAS No.:958261-94-4
Molecular Formula:C₂₇H₂₈BrNO₃S
Molecular Weight:526.494
Hs Code.:

Synonyms:N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Suppliers and Price of N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

There total 7 articles about N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 958261-93-3
9-bromo-2,3,6-trimethoxyphenanthrene-10-carbaldehyde

: 2014-77-9
1-methyl-2-(phenylsulfanyl)ethylamine

: 958261-94-4
N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Guidance literature:: 9-bromo-2,3,6-trimethoxyphenanthrene-10-carbaldehyde; 1-methyl-2-(phenylsulfanyl)ethylamine; With acetic acid; In tetrahydrofuran; at 20 ℃; for 1h;

With sodium cyanoborohydride; In tetrahydrofuran; at 20 ℃; for 0.166667h; Further stages.;
DOI:10.1016/j.tet.2007.08.030

Reference yield:

: 958261-92-2
N-methyl-9-bromo-2,3,6-trimethoxyphenanthrene-10-carboxamide

: 958261-94-4
N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: DIBAL-H / tetrahydrofuran; hexane / -20 - 20 °C

1.2: 101 mg / Cp₂Zr(H)Cl / 4 h / 20 °C

2.1: acetic acid / tetrahydrofuran / 1 h / 20 °C

2.2: 100 percent / NaBH₃CN / tetrahydrofuran / 0.17 h / 20 °C

With diisobutylaluminium hydride; acetic acid; In tetrahydrofuran; hexane;
DOI:10.1016/j.tet.2007.08.030

Reference yield:

: 2,3,6-trimethoxyphenanthrene-10-carboxylic acid chloride

: 958261-94-4
N-[1-methyl-2-(phenylsulfanyl)ethyl]-[9-bromo-2,3,6-trimethoxyphenanthren-10-yl]methylamine

Guidance literature:: Multi-step reaction with 5 steps

1.1: 660 mg / triethylamine / CH₂Cl₂ / 0 - 20 °C

2.1: TMEDA; sec-BuLi / tetrahydrofuran / 1 h / -78 °C

2.2: CBr₄ / tetrahydrofuran / -78 - 20 °C

3.1: TFA / 42 h / Heating

4.1: DIBAL-H / tetrahydrofuran; hexane / -20 - 20 °C

4.2: 101 mg / Cp₂Zr(H)Cl / 4 h / 20 °C

5.1: acetic acid / tetrahydrofuran / 1 h / 20 °C

5.2: 100 percent / NaBH₃CN / tetrahydrofuran / 0.17 h / 20 °C

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; diisobutylaluminium hydride; acetic acid; triethylamine; trifluoroacetic acid; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1016/j.tet.2007.08.030