n-Benzyl-2-(pyridin-2-yl)ethanamine

Base Information

• Chemical Name: n-Benzyl-2-(pyridin-2-yl)ethanamine
• CAS No.: 6312-25-0
• Molecular Formula: C14H16N2
• Molecular Weight: 212.294
• Hs Code.: 2933399090
• NSC Number: 42686
• DSSTox Substance ID: DTXSID50285724
• Wikidata: Q82021204
• Mol file: 6312-25-0.mol

Synonyms:6312-25-0;n-benzyl-2-(pyridin-2-yl)ethanamine;N-benzyl-2-pyridin-2-ylethanamine;N-Benzyl-2-pyridineethylamine;N-Benzyl-2-(pyridin-2-yl)ethan-1-amine;N-benzyl-2-pyridin-2-yl-ethanamine;NSC42686;N-BENZYL-2-PYRIDIN-2-YLETHYLAMINE;SCHEMBL6742452;DTXSID50285724;N-Benzyl-2-(2-pyridyl)-ethylamine;benzyl-(2-pyridin-2-yl-ethyl)amine;MFCD00089263;NSC-42686;AKOS000236123;SB78918;N-(phenylmethyl)-2-pyridin-2-ylethanamine;CS-0368110;FT-0766782

Chemical Property of n-Benzyl-2-(pyridin-2-yl)ethanamine

Chemical Property:

• Vapor Pressure: 0.000102mmHg at 25°C
• Refractive Index: 1.575
• Boiling Point: 337.9 °C at 760 mmHg
• Flash Point: 158.1 °C
• PSA: 24.92000
• Density: 1.053 g/cm³
• LogP: 2.80480
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 212.131348519
• Heavy Atom Count: 16
• Complexity: 176

Purity/Quality:

99% ^*data from raw suppliers

N-Benzyl-2-pyridineethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNCCC2=CC=CC=N2

Technology Process of n-Benzyl-2-(pyridin-2-yl)ethanamine

There total 7 articles about n-Benzyl-2-(pyridin-2-yl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.4%

2-(aminoethyl)pyridine (2706-56-1) + benzaldehyde (100-52-7) → N?[2?(2?pyridyl)ethyl]phenethylamine (6312-25-0)

Guidance literature:

2-(aminoethyl)pyridine; benzaldehyde; In methanol; at 20 ℃; for 1h;

With sodium tetrahydroborate; In methanol; at 20 ℃;

DOI:10.1007/s12257-016-0175-8

Reference yield: 72.0%

2-vinylpyridine (100-69-6,25014-15-7,27476-03-5,329041-71-6) + benzylamine (100-46-9) → N?[2?(2?pyridyl)ethyl]phenethylamine (6312-25-0)

Guidance literature:

With acetic acid; In methanol; for 40h; Heating;

DOI:10.1021/ja026047x

Reference yield:

2-vinylpyridine (100-69-6,25014-15-7,27476-03-5,329041-71-6) + benzylamine (100-46-9) → N?[2?(2?pyridyl)ethyl]phenethylamine (6312-25-0) + (N-benzyl)-bis-[2-(pyrid-2-yl)ethyl]amine (31582-29-3)

Guidance literature:

With betaine; sodium hydroxide; ortho-chlorobenzoic acid; In water; at 50 ℃; for 24h; Reagent/catalyst;

DOI:10.1007/s00706-020-02660-z

upstream raw materials:

2-vinylpyridine

benzylamine

1-phenyl-N-(2-(pyridin-2-yl)ethyl)methanimine

2-(aminoethyl)pyridine

Downstream raw materials:

N-{(pyrazol-1-yl)methyl}-N-benzyl-2-(pyridin-2-yl)ethanamine

3--N'-(2-phenylethyl)propanamide

3--N'-benzylpropanamide

(N-benzyl-N-ethyl-2-(2-pyridyl)ethylamine)

Refernces

• 1、 -. "COMPOSITION FOR DESTRUCTION OF MICROALGAE OR SPHAEROCARPUS". Paragraph 0192-0194. . Retrieved 2018/10/19.
• 2、 Singh, Ravindra,Lloret, Francesc,Mukherjee, Rabindranath. "Mono-and Di-chloro-bridged discrete dimers and trimers and mono-chloro-bridged 1d-coordination polymer of copper(II). Magneto-structural studies". . p. 1086 - 1094. Retrieved 2014/06/09.