Phenyl-2'-hydroxyethyl disulfide

Base Information

• Chemical Name: Phenyl-2'-hydroxyethyl disulfide
• CAS No.: 63369-64-2
• Molecular Formula: C8H10OS2
• Molecular Weight: 186.299
• Hs Code.: 2930909090
• Mol file: 63369-64-2.mol

Synonyms:Ethanol,2-(phenyldithio);

Chemical Property of Phenyl-2'-hydroxyethyl disulfide

Chemical Property:

• PSA: 70.83000
• LogP: 2.41920

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenyl-2'-hydroxyethyl disulfide

There total 3 articles about Phenyl-2'-hydroxyethyl disulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

thiophenol (108-98-5) + 2-hydroxyethanethiol (60-24-2) → 2-(phenyldisulfanyl)ethan-1-ol (63369-64-2)

Guidance literature:

With tris[2-phenylpyridinato-C²,N]iridium(III); In acetone; at 20 ℃; for 15h; Inert atmosphere; Sealed tube; Irradiation; Green chemistry;

DOI:10.1002/adsc.201800405

Reference yield: 70.5%

thiophenol (108-98-5) + 2-hydroxyethanethiol (60-24-2) → 2-(phenyldisulfanyl)ethan-1-ol (63369-64-2) + bis(2-hydroxyethyl) disulfide (1892-29-1) + diphenyldisulfane (882-33-7)

Guidance literature:

With tris[2-phenylpyridinato-C²,N]iridium(III); In acetone; at 20 ℃; Inert atmosphere; Sealed tube; Irradiation; Green chemistry;

DOI:10.1002/adsc.201800405

Reference yield: 45.0%

diphenyldisulfane (882-33-7) + 2-hydroxyethanethiol (60-24-2) → 2-(phenyldisulfanyl)ethan-1-ol (63369-64-2)

Guidance literature:

With pyridine; In methanol; at 20 ℃;

DOI:10.1002/chem.200501538

upstream raw materials:

diphenyldisulfane

2-hydroxyethanethiol

thiophenol

Downstream raw materials:

2-(phenyldisulfanyl)ethyl 4-nitrophenyl carbonate

N'-(2-phenyldisulfanylethyloxycarbonyl)-L-lysine

Refernces

• 1、 Dethe, Dattatraya H.,Srivastava, Aparna,Dherange, Balu D.,Kumar, B. Vijay. "Unsymmetrical Disulfide Synthesis through Photoredox Catalysis". supporting information. p. 3020 - 3025. Retrieved 2018/08/23.