Guaimesal

Base Information

Chemical Name:Guaimesal
CAS No.:81674-79-5
Molecular Formula:C16H14O5
Molecular Weight:286.284
Hs Code.:
UNII:K43273G1CW
DSSTox Substance ID:DTXSID00868622
Nikkaji Number:J33.101E
Wikidata:Q15633270
NCI Thesaurus Code:C65824
ChEMBL ID:CHEMBL2105115
Mol file:81674-79-5.mol

Synonyms:2-(2-methoxyphenoxy)-2-methyl-1,3-benzodioxan-4-one;guaimesal;MR 693;MR-693

Suppliers and Price of Guaimesal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Guaimesal
25mg
$ 326.00

TRC
Guaimesal
250mg
$ 475.00

American Custom Chemicals Corporation
GUAIMESAL 95.00%
5MG
$ 502.93

Total 11 raw suppliers

Chemical Property of Guaimesal

Chemical Property:

Vapor Pressure:1.86E-08mmHg at 25°C
Refractive Index:1.573
Boiling Point:454.7 °C at 760 mmHg
Flash Point:203.5 °C
PSA：53.99000
Density:1.262 g/cm³
LogP:2.99710
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:286.08412354
Heavy Atom Count:21
Complexity:385

Purity/Quality:

98%Min ^*data from raw suppliers

Guaimesal ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OC2=CC=CC=C2C(=O)O1)OC3=CC=CC=C3OC
Uses Guaimesal is a potential aspirin prodrug and is a degradation product of acetylsalicylic acid displaying similar effects.

Technology Process of Guaimesal

There total 4 articles about Guaimesal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90-05-1
2-methoxy-phenol

: 50-78-2,98201-60-6
aspirin

: 55482-89-8
Guaiaspir

: 81674-79-5
2-methyl-2-<2-(methoxy)phenoxy>-4H-1,3-benzodioxin-4-one

Guidance literature:: With trifluoroacetic anhydride; In benzene; for 10h; Ambient temperature;
DOI:10.1002/jps.2600800609

Reference yield:

: 90-05-1
2-methoxy-phenol

: 5538-51-2
O-acetylsalicyloyl chloride

: 55482-89-8
Guaiaspir

: 81674-79-5
2-methyl-2-<2-(methoxy)phenoxy>-4H-1,3-benzodioxin-4-one

Guidance literature:: With chloro-trimethyl-silane; triethylamine; Multistep reaction. Yields of byproduct given; 1.) chloroform, reflux, 2.) reflux;