1-Nonen-4-ol

Base Information

• Chemical Name: 1-Nonen-4-ol
• CAS No.: 35192-73-5
• Molecular Formula: C9H18 O
• Molecular Weight: 142.241
• NSC Number: 102783
• DSSTox Substance ID: DTXSID201015909
• Nikkaji Number: J401.965B
• Mol file: 35192-73-5.mol

Synonyms:4-Hydroxy-1-nonene;NSC 102783

Chemical Property of 1-Nonen-4-ol

Chemical Property:

• Vapor Pressure: 0.079mmHg at 25°C
• Boiling Point: 200.7°Cat760mmHg
• PKA: 15.24±0.20(Predicted)
• Flash Point: 77.6°C
• PSA: 20.23000
• Density: 0.836g/cm³
• LogP: 2.50370
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 142.135765193
• Heavy Atom Count: 10
• Complexity: 78.8

Purity/Quality:

99% ^*data from raw suppliers

1-Nonen-4-ol ^*data from reagent suppliers

Safty Information:

• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC(CC=C)O
• Uses: 1-Nonen-4-ol is a useful reagent for MnO2-promoted chemo- and regioselective preparation of β-hydroxyalkyl and Me ketones.

Technology Process of 1-Nonen-4-ol

There total 1 articles about 1-Nonen-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-[(1R,2R)-2-((R)-1-Allyl-hexyloxy)-1-methyl-2-phenyl-ethyl]-2,2,2-trifluoro-acetamide (183378-06-5) → 2,2,2-trifluoro-N-[(1R)-1-methyl-2-phenylethyl]acetamide (57573-45-2) + (R)-non-1-en-4-ol (35192-73-5,106756-94-9,121842-18-0,91525-93-8)

Guidance literature:

With ammonia; sodium; In tetrahydrofuran;

Reference yield: 100.0%

non-1-en-4-ol (35192-73-5) + benzyl bromide (100-39-0) → (RS)-4-(benzyloxy)non-1-ene (274257-04-4)

Guidance literature:

non-1-en-4-ol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 1h;

benzyl bromide; In tetrahydrofuran; mineral oil; at 20 ℃; for 18h;

DOI:10.1021/jo301830j

Reference yield: 96.0%

(R)-methoxytrifluoromethylphenylacetyl chloride (20445-33-4,39637-99-5) + (S)-4-hydroxy-1-nonene (35192-73-5,91525-93-8,106756-94-9,121842-18-0) → C19H25F3O3

Guidance literature:

With pyridine; In dichloromethane; at 25 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jacs.8b12816

upstream raw materials:

N-[(1R,2R)-2-((R)-1-Allyl-hexyloxy)-1-methyl-2-phenyl-ethyl]-2,2,2-trifluoro-acetamide

Downstream raw materials:

Benzoic acid 1-allyl-hexyl ester

(RS)-4-(benzyloxy)non-1-ene

2-Pentyl-4-fluorotetrahydrofuran

(2S,4R,6S)-4-acetoxy-2-(3',4'-diacetoxyphenyl)-6-pentyltetrahydropyran

Refernces