1-[(Benzyloxy)carbonyl]-2-methyl-L-proline

Base Information

Chemical Name:1-[(Benzyloxy)carbonyl]-2-methyl-L-proline
CAS No.:63399-71-3
Molecular Formula:C14H17NO4
Molecular Weight:263.293
Hs Code.:
Mol file:63399-71-3.mol

Synonyms:1-[(benzyloxy)carbonyl]-2-methyl-L-proline;N-(benzyloxycarbonyl)-(S)-2-methylproline;(S)-1-(benzyloxycarbonyl)-2-methylpyrrolidine-2-carboxylic acid;1,2-Pyrrolidinedicarboxylic acid,2-methyl-,1-(phenylmethyl) ester,(S);benzyloxycarbonyl-D,L-2-methylproline;

Suppliers and Price of 1-[(Benzyloxy)carbonyl]-2-methyl-L-proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
1-Cbz-2-methyl-L-proline 97%
5g
$ 825.00

ACHEMBLOCK
1-Cbz-2-methyl-L-proline 95%
1G
$ 335.00

ACHEMBLOCK
1-Cbz-2-methyl-L-proline 95%
250MG
$ 165.00

Total 6 raw suppliers

Chemical Property of 1-[(Benzyloxy)carbonyl]-2-methyl-L-proline

Chemical Property:

PSA：69.67000
LogP:0.86550

Purity/Quality:

98% ^*data from raw suppliers

1-Cbz-2-methyl-L-proline 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[(Benzyloxy)carbonyl]-2-methyl-L-proline

There total 2 articles about 1-[(Benzyloxy)carbonyl]-2-methyl-L-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 42856-71-3
(S)-2-methylpyrrolidine-2-carboxylic acid

: 501-53-1,94274-21-2
benzyl chloroformate

: 63399-71-3
(S)-1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid

Guidance literature:: With sodium carbonate; In water; at 50 ℃; for 216h;
DOI:10.1021/jo701746w

Reference yield:

: 63399-73-5
α-methyl-L-proline hydrobromide

: 501-53-1,94274-21-2
benzyl chloroformate

: 63399-71-3
(S)-1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid

Guidance literature:: With sodium hydroxide; for 3.5h; 5 to 10 deg C;

Reference yield: 94.0%

: 63399-71-3
(S)-1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid

: 1031890-09-1
benzyl (S)-2-carbamoyl-2-methylpyrrolidine-1-carboxylate

Guidance literature:: (S)-1-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid; With chloroformic acid ethyl ester; triethylamine; In chloroform; at 0 ℃; for 2h;

With ammonia; In chloroform; water; for 3h; Further stages.;
DOI:10.1002/ejoc.200700834