3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride

Base Information

• Chemical Name: 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride
• CAS No.: 19382-49-1
• Molecular Formula: C5H8 N2 O2 S . Cl H
• Molecular Weight: 196.658
• Hs Code.: 2934999090
• Mol file: 19382-49-1.mol

Synonyms:2,4-Thiazolidinedione,3-(2-aminoethyl)-, hydrochloride (6CI,7CI); 2,4-Thiazolidinedione, 3-(2-aminoethyl)-,monohydrochloride (8CI,9CI); 3-(2-Aminoethyl)thiazolidine-2,4-dionehydrochloride

Chemical Property of 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride

Chemical Property:

• Vapor Pressure: 0.00267mmHg at 25°C
• Melting Point: 227-228 °C(Solv: ethanol (64-17-5))
• Boiling Point: 286.3°Cat760mmHg
• Flash Point: 126.9°C
• PSA: 88.70000
• Density: g/cm³
• LogP: 1.08070

Purity/Quality:

98%min ^*data from raw suppliers

3-(2-Aminoethyl)-1,3-thiazolidine-2,4-dioneHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride

There total 3 articles about 3-(2-aminoethyl)thiazolidine-2,4-dione hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

ethyl [(4,5-dihydro-2-imidazolyl)thio]acetate hydrochloride (91774-37-7) → 3-(2-aminoethyl)-2,4-thiazolidinedione hydrochloride (19382-49-1)

Guidance literature:

With hydrogenchloride; In ethanol; for 3h; Heating;

DOI:10.1007/s10593-006-0075-5

Reference yield: 43.0%

N,N'-ethylenethiourea (96-45-7) + chloroacetic acid (79-11-8) → 3-(2-aminoethyl)-2,4-thiazolidinedione hydrochloride (19382-49-1)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1007/s10593-006-0075-5

Reference yield: 10.0%

N,N'-ethylenethiourea (96-45-7) + butyl chloroacetate (590-02-3) → 3-(2-aminoethyl)-2,4-thiazolidinedione hydrochloride (19382-49-1)

Guidance literature:

In ethanol; for 3h; Heating;

DOI:10.1007/s10593-006-0075-5

upstream raw materials:

N,N'-ethylenethiourea

butyl chloroacetate

chloroacetic acid

ethyl [(4,5-dihydro-2-imidazolyl)thio]acetate hydrochloride

Refernces