96-45-7

Basic information

• Product Name: Ethlenethiourea
• Synonyms: 1,3-ethylene-2-thio-ure;1,3-Ethylene-2-thiourea;2H-Imidazole-2-thione, tetrahydro-;2-imadazoline-2-thiol;2-Imidazolidinethione ethylene thiourea;2-Imidazoline-2-thiol;2-Imidozolidimethione;2-Mercapto-2-imidazoline
• CAS NO: 96-45-7
• Molecular Formula: C₃H₆N₂S
• Molecular Weight: 102.16
• EINECS: 202-506-9
• Product Categories: Organics;rubber additive;rubber auxiliary;rubber vulcanizing accelerator;Peroxidase Inhibitors;and Substrates;Biochemicals and Reagents;Building Blocks;Chemical Synthesis;Enzyme Inhibitors;Enzyme Inhibitors by Enzyme;Enzymes;Inhibitors;Organic Building Blocks;P to Q;Sulfur Compounds;Thioureas;chlorinated polyethylene (CPE) rubber vulcanizing accelerator agent;elastomer accelerator
• Mol File: 96-45-7.mol
• Article Data: 42

Chemical Properties

• Melting Point: 196-200 °C(lit.)
• Boiling Point: 148.3 °C at 760 mmHg
• Flash Point: 252 °C
• Appearance: White/Powder
• Density: 1.41~1.45
• Vapor Pressure: 6.279mmHg at 25°C
• Refractive Index: 1.5500 (estimate)
• Storage Temp.: 0-6°C
• Solubility: 8g/l
• PKA: 15.01±0.20(Predicted)
• Water Solubility: 19 g/L (20 ºC)
• Merck: 14,3803
• BRN: 106275
• CAS DataBase Reference: Ethlenethiourea(CAS DataBase Reference)
• NIST Chemistry Reference: Ethlenethiourea(96-45-7)
• EPA Substance Registry System: Ethlenethiourea(96-45-7)

Safety Data

• Hazard Codes: T
• Statements: 61-22-48/23/25-40
• Safety Statements: 53-45
• RIDADR: 2811
• WGK Germany: 2
• RTECS: NI9625000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 96-45-7(Hazardous Substances Data)

Usage

Description

Ethylenethiourea, a thiourea derivative, is a rubber chemical. It has caused contact dermatitis mainly in rubber workers.

Chemical Properties

Ethylene thiourea is a white to light green, needle-like crystalline solid with a faint amine odor. It is very soluble in hot water;slightly soluble in cold water, methanol, ethanol, ethylene glycol, pyridine, acetic acid, and naphtha; and insoluble in acetone, ether, chloroform, and benzene.When heated to decomposition, ethylene thiourea emits toxic fumes of nitrogen oxides (NOx) and sulfur oxides (SOx). Ethylene thiourea is available in the United States as crystals, as a powder, as an 80% dispersion of the powder in oil, or encapsulated in a matrix of compatible elastomers.

Uses

Different sources of media describe the Uses of 96-45-7 differently. You can refer to the following data:
1. Accelerator in the curing of polychloroprene (neoprene) and polyacrylate rubber; intermediate in the manufacture of antioxidants, insecticides, fungicides, dyes, pharmaceuticals, and synthetic resins
2. elastomer accelerator;chlorinated polyethylene (CPE) rubber vulcanizing accelerator agent. Ethylene thiourea is used primarily as an accelerator for vulcanizing polychloroprene (Neoprene?) and polyacrylate rubbers. Neoprene rubbers are used almost exclusively in industrial applications，e.g.. for mechanical and automotive products, in wire and cable production, in construction，and in adhesives. Polyacrylate rubbers are used in products such as seals, o-rings, and gaskets for automotive and aircraft applications. Ethylene thiourea is used in the manufacture of ethylene-bisdithiocarbamate pesticides, such as Maneb?, Mancozeb?, Metiram?,and Zineb?.Ethylene thiourea is also used in electroplating baths, as an intermediate in antioxidant production, in dyes， pharmaceuticals，and synthetic resins. However, there is no evidence that the compound is used commercially for any of these purposes (IARC V.7, 1974; Sax, 1987).
3. 2-Imidazolidinethione is a pesticide used in production of fruits and vegetables. It is also used as a new contrast agent for MRI studies based on proton chemical exchange dependent saturation transfe r. 2-Imidazolidinethione is also a corrosion inhibitor due to the adsorption of the mol. species.

General Description

White to pale green crystals or an off-white solid. Odorless when pure, but technical product may have an amine odor.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

Ethlenethiourea may be sensitive to prolonged exposure to light. Incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. May react with acids to liberate hydrogen sulfide.

Hazard

Questionable carcinogen.

Health Hazard

Ethylene thiourea (ETU) is an antithyroid substance and animal carcinogen.

Fire Hazard

Ethylene thiourea is combustible.

Flammability and Explosibility

Nonflammable

Contact allergens

Ethylene thiourea, a thiourea derivative, is a rubber chemical. It caused contact dermatitis mainly in rubber workers.

Potential Exposure

Ethylene thiourea is used extensively as an accelerator in the curing of polychloroprene (Neoprene) and other elastomers; as a vulcanizing accelerator in rubber processing; in electroplating baths. In addition, exposure to ethylene thiourea also results from the very widely used ethylene bisdithiocarbamate fungicides. Ethylene thiourea may be present as a contaminant in the ethylene bisdithiocarbamate fungicides and can also be formed when food containing the fungicides is cooked

Carcinogenicity

Ethylene thiourea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Purification Methods

Crystallise it from EtOH or amyl alcohol. [Beilstein 24 III/IV 22.]

Incompatibilities

Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid anhydrides, and acrolein

Waste Disposal

Incineration in a furnace equipped with afterburner and scrubber.

InChI:InChI=1/C3H6N2S/c6-5-2-1-4-3-5/h3,6H,1-2H2

Upstream product

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Downstream Products

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Relevant articles and documents

Solar-light driven photocatalytic conversion of p-nitrophenol to p-aminophenol on CdS nanosheets and nanorods

A simple synthetic protocol devoid of toxic surfactants was applied for the synthesis of CdS nanosheets and nanorods by thermolyzing bis(4-benzylpiperadine-1-carbodithioate-κ2 S, S′) cadmium(II) (1) and propane-1,3-diyl bis (piperidincarbamodithioate)cadmium(II) (2) using ethylenediamine (en) as a solvent. The as obtained products were characterized by TEM, PXRD, and UV–Visible spectroscopy. The nanosheets (1) and nanorods (2) were confirmed by HR-TEM with a lattice spacing of 0.33?nm which corresponds to the 002 plane of hexagonal CdS, observations in consonance with XRD. Based upon the band gap obtained from UV–Vis, 2.91?eV (nanosheets) and 2.65?eV (nanorods), these nanoparticles (NPs) were used as solar light driven photocatalyst for the conversion of p-nitrophenol to p-aminophenol. The nanorods (8?min) were found slightly more efficient than nanosheets (10?min), and the conversion efficiency of both remained above 92% even after 3rd cycle without any structural damage as revealed by the afterward PXRD. The better catalytic activity of both morphologies can be attributed to quantum size effect and good optical absorbance.

Synthesis method of heterocyclic compound containing bis (trimethylsilyl)

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