Halofuginone hydrobromide

Base Information Edit

Chemical Name:Halofuginone hydrobromide
CAS No.:17395-31-2
Molecular Formula:2BrH*C₁₆H₁₇BrClN₃O₃
Molecular Weight:576.51
Hs Code.:
European Community (EC) Number:241-422-7,694-602-6
DSSTox Substance ID:DTXSID10938441
NCI Thesaurus Code:C2656
ChEMBL ID:CHEMBL559362
Mol file:17395-31-2.mol

Synonyms:(+)-halofuginone;(+-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone;(+-)-trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone monohydrobromide;(-)-halofuginone;(-)-halofuginone hydrobromide;4(3H)-quinazolinone, 7-bromo-6-chloro-3-(3-((2R,3S)-3-hydroxy-2-piperidinyl)-2-oxopropyl)-, hydrochloride (1:1), rel-;4(3H)-quinazolinone, 7-bromo-6-chloro-3-(3-((2S,3R)-3-hydroxy-2-piperidinyl)-2-oxopropyl)-, hydrobromide (1:1);4(3H)-quinazolinone, 7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-, hydrobromide, trans-(+-)-;4(3H)-quinazolinone, 7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-, trans-, mono(2-hydroxypropanoate)(salt);6-chloro-7-bromo-(+)-febrifugine;6-chloro-7-bromofebrifugine;7-bromo-6-chloro-3,3-(3-hydroxy-2-piperidyl)acetonyl-4(3H)-quinazolinone-hydrolactate;7-bromo-6-chloro-3-(3-((2R,3S)-3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3H)-quinazolinone;7-bromo-6-chloro-3-(3-((2S,3R)-3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3H)-quinazolinone;7-bromo-6-chloro-3-(3-((2S,3R)-3-hydroxy-2-piperidyl)-2-oxo-propyl)quinazolin-4-one hydrobromide;7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidinyl)-2-oxopropyl)-4(3H)-quinazolinone;7-bromo-6-chlorofebrifugine;Cebegine;chloro-bromofebrifugine;chlorobromofebrifugine;Halagon;Halocur;halofuginon;halofuginone;halofuginone HBr;halofuginone HCl;halofuginone hydrobromide;halofuginone hydrobromide, (-)-;halofuginone hydrochloride;halofuginone lactate;halofuginone monohydrobromide;halofuginone monohydrochloride;halofuginone, (+)-;halofuginone, (-)-;halofunginone;RU 19110;RU-19110;RU19110;Stenorol;trans-7-bromo-6-chloro-3-(3-(3-hydroxy-2-piperidyl)-acetonyl)-4(3H)-quinazolinone

Suppliers and Price of Halofuginone hydrobromide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 11 raw suppliers

Chemical Property of Halofuginone hydrobromide Edit

Chemical Property:

Vapor Pressure:4.84E-15mmHg at 25°C
Boiling Point:595.8°Cat760mmHg
Flash Point:314.1°C
PSA：84.22000
Density:g/cm³
LogP:3.17140
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:494.93829
Heavy Atom Count:25
Complexity:533

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br
Recent ClinicalTrials:Halofuginone Hydrobromide in Treating Patients With HIV-Related Kaposi's Sarcoma

Technology Process of Halofuginone hydrobromide

There total 73 articles about Halofuginone hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%