Technology Process of Benzenepropanoic acid, a-methyl-,
2-methylene-4-phenyl-4-[(phenylmethyl)amino]butyl ester
There total 9 articles about Benzenepropanoic acid, a-methyl-,
2-methylene-4-phenyl-4-[(phenylmethyl)amino]butyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
acetic acid; tetramethylammonium triacetoxyborohydride;
In
1,2-dichloro-ethane;
at 20 ℃;
for 89h;
DOI:10.1039/b303752e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 97 percent / pyridine / CH2Cl2 / 0.58 h / 20 °C
2.1: BF3*OEt2 / CH2Cl2 / 0.33 h / 20 °C
2.2: 380 mg / CH2Cl2 / 3 h / -20 - 20 °C
3.1: 93 percent / TFA / CH2Cl2 / 2.5 h / 20 °C
4.1: 76 percent / AcOH; Me4N(AcO)3BH / 1,2-dichloro-ethane / 89 h / 20 °C
With
pyridine; boron trifluoride diethyl etherate; acetic acid; trifluoroacetic acid; tetramethylammonium triacetoxyborohydride;
In
dichloromethane; 1,2-dichloro-ethane;
2.2: imino-Sakurai reaction;
DOI:10.1039/b303752e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: BF3*OEt2 / CH2Cl2 / 0.33 h / 20 °C
1.2: 380 mg / CH2Cl2 / 3 h / -20 - 20 °C
2.1: 93 percent / TFA / CH2Cl2 / 2.5 h / 20 °C
3.1: 76 percent / AcOH; Me4N(AcO)3BH / 1,2-dichloro-ethane / 89 h / 20 °C
With
boron trifluoride diethyl etherate; acetic acid; trifluoroacetic acid; tetramethylammonium triacetoxyborohydride;
In
dichloromethane; 1,2-dichloro-ethane;
1.2: imino-Sakurai reaction;
DOI:10.1039/b303752e