2-Naphthaleneethanol

Base Information

• Chemical Name: 2-Naphthaleneethanol
• CAS No.: 1485-07-0
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Hs Code.: 2906299090
• European Community (EC) Number: 216-061-3
• NSC Number: 21040
• UNII: 35GBR3X2UM
• DSSTox Substance ID: DTXSID10163998
• Nikkaji Number: J134A
• Wikidata: Q72493504
• Mol file: 1485-07-0.mol

Synonyms:1-(2-naphthyl)ethanol

Chemical Property of 2-Naphthaleneethanol

Chemical Property:

• Vapor Pressure: 0.000268mmHg at 25°C
• Melting Point: 66-68 °C(lit.)
• Refractive Index: 1.636
• Boiling Point: 309.846 °C at 760 mmHg
• PKA: 14.84±0.10(Predicted)
• Flash Point: 150.648 °C
• PSA: 20.23000
• Density: 1.119 g/cm³
• LogP: 2.37460
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 172.088815002
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

2-NaphthaleneEthanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)CCO

Technology Process of 2-Naphthaleneethanol

There total 40 articles about 2-Naphthaleneethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diisopropyl-1H,1H,2H,2H-perfluorododecylsilyl 2-(2-naphthyl)ethyl ether (374928-94-6) → naphthalen-2-ethanol (1485-07-0)

Guidance literature:

With fluorosilicic acid; In methanol; acetonitrile; for 144h;

DOI:10.1021/ja011716c

Reference yield: 99.0%

diisopropyl-1H,1H,2H,2H-perfluorodecylsilyl 2-(2-naphthyl)ethyl ether (374928-84-4) → naphthalen-2-ethanol (1485-07-0)

Guidance literature:

With fluorosilicic acid; In acetonitrile; for 24h;

DOI:10.1021/ja011716c

Reference yield: 98.0%

methyl 2-naphthylacetate (2876-71-3) → naphthalen-2-ethanol (1485-07-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; at 0 ℃; for 2h;

upstream raw materials:

2-naphthylacetic acid

oxirane

2-naphthalenylmagnesium bromide

2-naphthylethylene

Downstream raw materials:

2-naphthylethylene

2-(2-bromoethyl)naphthalene

2-ethylnaphthalene

2-(2-naphthyl)ethylamine hydrochloride

Refernces

• 1、 Kim, Dong Wook,Song, Choong Eui,Chi, Dae Yoon. "New method of fluorination using potassium fluoride in ionic liquid: Significantly enhanced reactivity of fluoride and improved selectivity". . p. 10278 - 10279. Retrieved 2002.
• 2、 Banks, Tony M.,Clay, Samuel F.,Glover, Stephen A.,Schumacher, Rhiannon R.. "Mutagenicity of N-acyloxy-N-alkoxyamides as an indicator of DNA intercalation part 1: Evidence for naphthalene as a DNA intercalator". . p. 3699 - 3714. Retrieved 2016.
• 3、 Karrer et al.. "-". . p. 585,586. Retrieved 1940.
• 4、 Mayr, Stefanie,Marin-Luna, Marta,Zipse, Hendrik. "Size-Driven Inversion of Selectivity in Esterification Reactions: Secondary Beat Primary Alcohols". . p. 3456 - 3489. Retrieved 2021/03/01.
• 5、 -. "AMINOPEPTIDASE A INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME". Page/Page column 69. . Retrieved 2020/06/10.