1,4-Bis(2-fluorophenyl)piperazine

Base Information

Chemical Name:1,4-Bis(2-fluorophenyl)piperazine
CAS No.:63523-84-2
Molecular Formula:C16H16F2N2
Molecular Weight:274.313
Hs Code.:
DSSTox Substance ID:DTXSID30494014
Wikidata:Q82341065

Synonyms:1,4-Bis(2-fluorophenyl)piperazine;63523-84-2;DTXSID30494014

Suppliers and Price of 1,4-Bis(2-fluorophenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1,4-Bis(2-fluorophenyl)piperazine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:274.12815484
Heavy Atom Count:20
Complexity:275

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1C2=CC=CC=C2F)C3=CC=CC=C3F

Technology Process of 1,4-Bis(2-fluorophenyl)piperazine

There total 2 articles about 1,4-Bis(2-fluorophenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-85-0
piperazine

: 1072-85-1
o-fluorobromobenzene

: 462-06-6
fluorobenzene

: 63523-84-2
1,4-bis-(2-fluoro-phenyl)-piperazine

: 1011-15-0
1-(o-fluorophenyl)piperazine

Guidance literature:: With sodium t-butanolate; palladium bis(dibenzylideneacetone)palladium⁽⁰⁾; tri-tert-butyl phosphine; In o-xylene; at 120 ℃; Yield given. Yields of byproduct given;
DOI:10.1016/S0040-4039(97)10659-1