2-Benzoylthiophene-3-carbonyl chloride

Base Information

Chemical Name:2-Benzoylthiophene-3-carbonyl chloride
CAS No.:63600-02-2
Molecular Formula:C12H7ClO2S
Molecular Weight:250.705
Hs Code.:
DSSTox Substance ID:DTXSID90495380
Wikidata:Q82343447

Synonyms:2-Benzoylthiophene-3-carbonyl chloride;63600-02-2;DTXSID90495380

Suppliers and Price of 2-Benzoylthiophene-3-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Benzoylthiophene-3-carbonyl chloride

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:249.9855283
Heavy Atom Count:16
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=C(C=CS2)C(=O)Cl

Technology Process of 2-Benzoylthiophene-3-carbonyl chloride

There total 3 articles about 2-Benzoylthiophene-3-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30011-75-7
2-(phenylcarbonyl)thiophene-3-carboxylic acid

: 63600-02-2
2-Benzoylthiophen-3-carbonsaeurechlorid

Guidance literature:: With chloroformic acid ethyl ester; In tetrahydrofuran; at 0 ℃; for 2h;
DOI:10.1016/j.tet.2012.09.050

Reference yield:

: 88-13-1
3-Thiophene carboxylic acid

: 63600-02-2
2-Benzoylthiophen-3-carbonsaeurechlorid

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropyl amide / tetrahydrofuran / 2 h / 0 - 20 °C

2: chloroformic acid ethyl ester / tetrahydrofuran / 2 h / 0 °C

With chloroformic acid ethyl ester; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/j.tet.2012.09.050

Reference yield:

: 100-52-7
benzaldehyde

: 63600-02-2
2-Benzoylthiophen-3-carbonsaeurechlorid

Guidance literature:: Multi-step reaction with 2 steps

1: lithium diisopropyl amide / tetrahydrofuran / 2 h / 0 - 20 °C

2: chloroformic acid ethyl ester / tetrahydrofuran / 2 h / 0 °C

With chloroformic acid ethyl ester; lithium diisopropyl amide; In tetrahydrofuran;
DOI:10.1016/j.tet.2012.09.050