2-Propenoic acid, 3-(4-hydroxyphenyl)-, 3-(4-hydroxyphenyl)-2-propenyl ester

Base Information

• Chemical Name: 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 3-(4-hydroxyphenyl)-2-propenyl ester
• CAS No.: 63644-63-3
• Molecular Formula: C18H16O4
• Molecular Weight: 296.323
• Mol file: 63644-63-3.mol

Synonyms:

Chemical Property of 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 3-(4-hydroxyphenyl)-2-propenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 3-(4-hydroxyphenyl)-2-propenyl ester

There total 3 articles about 2-Propenoic acid, 3-(4-hydroxyphenyl)-, 3-(4-hydroxyphenyl)-2-propenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(E)-3-(4-Acetoxy-phenyl)-acrylic acid (E)-3-(4-acetoxy-phenyl)-allyl ester (72704-07-5) → 4-coumaryl 4-coumarate (63644-63-3)

Guidance literature:

With hydrazinium monoacetate; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1039/c3ra42818d

Reference yield:

C14H14O6 → 4-coumaryl 4-coumarate (63644-63-3)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / ethyl acetate; N,N-dimethyl-formamide / 0 °C / Inert atmosphere

2: triethylamine; dmap / 1.5 h / 0 °C

3: hydrazinium monoacetate / N,N-dimethyl-formamide / 1 h / 20 °C

With dmap; sodium tetrahydroborate; hydrazinium monoacetate; triethylamine; In ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1039/c3ra42818d

Reference yield:

acetic acid 4-(2-chlorocarbonylvinyl)phenyl ester + 1-hydroxy-3-(4-acetoxyphenyl)-2-propen (1202495-53-1) → 4-coumaryl 4-coumarate (63644-63-3)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine; dmap / 1.5 h / 0 °C

2: hydrazinium monoacetate / N,N-dimethyl-formamide / 1 h / 20 °C

With dmap; hydrazinium monoacetate; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1039/c3ra42818d

upstream raw materials:

1-hydroxy-3-(4-acetoxyphenyl)-2-propen

(E)-3-(4-Acetoxy-phenyl)-acrylic acid (E)-3-(4-acetoxy-phenyl)-allyl ester

Downstream raw materials:

(-)-trans-Hinokiresinol

(+)-(7R,E)-hinokiresinol

(+)-Nyasol