1-(3-Amino-5-bromobenzofuran-2-yl)ethanone

Base Information

Chemical Name:1-(3-Amino-5-bromobenzofuran-2-yl)ethanone
CAS No.:636992-53-5
Molecular Formula:C10H8BrNO2
Molecular Weight:254.083
Hs Code.:2932999099
DSSTox Substance ID:DTXSID30450559
Wikidata:Q82270343

Synonyms:1-(3-Amino-5-bromobenzofuran-2-yl)ethanone;636992-53-5;1-(3-amino-5-bromobenzofuran-2-yl)ethan-1-one;SCHEMBL4504641;DTXSID30450559;UVQLWEREHFLAGA-UHFFFAOYSA-N;AKOS003827576;1-(3-amino-5-bromo-1-benzofuran-2-yl)ethan-1-one;1-(3-AMINO-5-BROMO-1-BENZOFURAN-2-YL)ETHANONE

Suppliers and Price of 1-(3-Amino-5-bromobenzofuran-2-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(3-Amino-5-bromobenzofuran-2-yl)ethanone 95+%
1g
$ 464.00

Chemenu
1-(3-amino-5-bromobenzofuran-2-yl)ethan-1-one 95%
1g
$ 439.00

Alichem
1-(3-Amino-5-bromobenzofuran-2-yl)ethanone
1g
$ 379.00

Total 2 raw suppliers

Chemical Property of 1-(3-Amino-5-bromobenzofuran-2-yl)ethanone

Chemical Property:

PSA：56.23000
LogP:3.56130
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:252.97384
Heavy Atom Count:14
Complexity:246

Purity/Quality:

≥99% ^*data from raw suppliers

1-(3-Amino-5-bromobenzofuran-2-yl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C2=C(O1)C=CC(=C2)Br)N

Technology Process of 1-(3-Amino-5-bromobenzofuran-2-yl)ethanone

There total 6 articles about 1-(3-Amino-5-bromobenzofuran-2-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.36%

: 40530-18-5
5-bromo-2-hydroxybenzonitrile

: 78-95-5
chloroacetone

: 636992-53-5
1-(3-amino-5-bromo-benzofuran-2-yl)-ethanone

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 2h;

Reference yield: 90.4%

: 295346-39-3
5-bromo-2-(2-oxopropoxy)benzonitrile

: 636992-53-5
1-(3-amino-5-bromo-benzofuran-2-yl)-ethanone

Guidance literature:: With triethylamine; at 90 ℃; for 5h;
DOI:10.1039/b312682j

Reference yield:

: 611-20-1
salicylonitrile

: 636992-53-5
1-(3-amino-5-bromo-benzofuran-2-yl)-ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 86.4 percent / K₂CO₃ / acetone / 6 h / 25 °C

2: 96.8 percent / NBS; AlCl₃ / acetonitrile / 1 h / 24 °C

3: 90.4 percent / Et₃N / 5 h / 90 °C

With N-Bromosuccinimide; aluminium trichloride; potassium carbonate; triethylamine; In acetone; acetonitrile;
DOI:10.1039/b312682j