2H-indeno[2,1-c]pyridazine-3,9-dione

Base Information

• Chemical Name: 2H-indeno[2,1-c]pyridazine-3,9-dione
• CAS No.: 100595-21-9
• Molecular Formula: C₁₁H₆N₂O₂
• Molecular Weight: 198.181
• DSSTox Substance ID: DTXSID30143414
• Wikidata: Q83007270
• Mol file: 100595-21-9.mol

Synonyms:2H-indeno[2,1-c]pyridazine-3,9-dione;100595-21-9;2H-Indeno(2,1-c)pyridazine-3,9-dione;3,9-Dioxo-2H-indeno(2,1-c)pyridazine;9-Oxo-indeno(2,1-c)-3(2H)-pyridazinone;DTXSID30143414;LS-81884

Chemical Property of 2H-indeno[2,1-c]pyridazine-3,9-dione

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.54g/cm³
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 198.042927438
• Heavy Atom Count: 15
• Complexity: 409

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC(=O)NN=C3C2=O

Technology Process of 2H-indeno[2,1-c]pyridazine-3,9-dione

There total 3 articles about 2H-indeno[2,1-c]pyridazine-3,9-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.4%

9H-indeno<2,1-c>-3(2H)-pyridazinone (100595-19-5) → 9-oxo-indeno<2,1-c>-3(2H)-pyridazinone (100595-21-9)

Guidance literature:

With chromium(VI) oxide; In acetic acid; for 2h; Heating;

Reference yield:

2-indanone-1-acetic acid ethyl ester (29983-59-3) → 9-oxo-indeno<2,1-c>-3(2H)-pyridazinone (100595-21-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 69 percent / hydrazine hydrate, acetic acid / ethanol / 18 h / Heating

2: 51.4 percent / CrO₃ / acetic acid / 2 h / Heating

With chromium(VI) oxide; hydrazine hydrate; acetic acid; In ethanol; acetic acid;

Reference yield:

9H-indeno<2,1-c>-2H-4,4a-dihydropyrazin-3-one (100595-18-4) → 9-oxo-indeno<2,1-c>-3(2H)-pyridazinone (100595-21-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / bromine / acetic acid / 2 h / Heating

2: 51.4 percent / CrO₃ / acetic acid / 2 h / Heating

With chromium(VI) oxide; bromine; In acetic acid;

upstream raw materials:

9H-indeno<2,1-c>-3(2H)-pyridazinone

2-indanone-1-acetic acid ethyl ester

9H-indeno<2,1-c>-2H-4,4a-dihydropyrazin-3-one