Technology Process of 10-Methoxy-1,4,6,9-tetramethylpyrido[3,2-g]quinoline-2,8(1h,9h)-dione
There total 7 articles about 10-Methoxy-1,4,6,9-tetramethylpyrido[3,2-g]quinoline-2,8(1h,9h)-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate; XPhos;
In
isopropyl alcohol;
at 110 ℃;
for 16h;
Inert atmosphere;
Sealed tube;
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); potassium carbonate; XPhos;
In
isopropyl alcohol;
at 110 ℃;
for 16h;
Inert atmosphere;
DOI:10.1021/ja100610m
- Guidance literature:
-
Multi-step reaction with 4 steps
1: Iodine monochloride / dichloromethane / 20 °C / Cooling with ice
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / dimethyl sulfoxide / 24.08 h / 80 °C / Inert atmosphere; Schlenk technique
3: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,2-dimethoxyethane; water / 3 h / 80 °C / Inert atmosphere; Schlenk technique
4: potassium carbonate; XPhos / isopropyl alcohol / 16 h / 110 °C / Inert atmosphere; Sealed tube
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; Iodine monochloride; potassium carbonate; XPhos;
In
1,2-dimethoxyethane; dichloromethane; water; dimethyl sulfoxide; isopropyl alcohol;
4: |Suzuki Coupling;
