Ethacizine

Base Information

Chemical Name:Ethacizine
CAS No.:33414-33-4
Molecular Formula:C₂₂H₂₇N₃O₃S
Molecular Weight:413.541
Hs Code.:
NSC Number:621878
UNII:FE5SPV1Z6G
DSSTox Substance ID:DTXSID50187057
Nikkaji Number:J33.907E
Wikipedia:Ethacizine
Wikidata:Q15408408
Metabolomics Workbench ID:154436
ChEMBL ID:CHEMBL1997663
Mol file:33414-33-4.mol

Synonyms:10-(3-(diethylamino)-1-oxopropyl)-10H-(phenothiazin-2-yl)carbamic acid ethyl ester;2-(ethoxycarbonylamino)-10-(3-(diethylamino)propionyl)phenothiazine;etacizin;etacyzine;etatsizin;etatsizine;ethacizine;NIK 244;NIK0244

Suppliers and Price of Ethacizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Ethacizine

Chemical Property:

Vapor Pressure:2.67E-13mmHg at 25°C
Melting Point:106-107 °C
Boiling Point:576.7°Cat760mmHg
PKA:12.88±0.20(Predicted)
Flash Point:302.6°C
PSA：87.18000
Density:1.239g/cm³
LogP:5.25420
XLogP3:4.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:413.17731291
Heavy Atom Count:29
Complexity:557

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCC(=O)N1C2=CC=CC=C2SC3=C1C=C(C=C3)NC(=O)OCC

Technology Process of Ethacizine

There total 4 articles about Ethacizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34749-22-9
2-Carbethoxyamino-10-(β-chloropropionyl)phenothiazine

: 109-89-7
diethylamine

: 33414-33-4
2-Carbethoxyamino-10-(β-diethylaminopropionyl)phenothiazine

Guidance literature:: In toluene;
DOI:10.1007/BF00758847

Reference yield:

: 34749-22-9
2-Carbethoxyamino-10-(β-chloropropionyl)phenothiazine

: 33414-33-4
2-Carbethoxyamino-10-(β-diethylaminopropionyl)phenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / triethylamine / toluene / 2 h / Heating

2: 3.5 h / Heating

With triethylamine; In toluene;
DOI:10.1007/BF00758818

Reference yield:

: 37711-29-8
Phenothiazine-2-carbamic acid ethyl ester

: 33414-33-4
2-Carbethoxyamino-10-(β-diethylaminopropionyl)phenothiazine

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / benzene / 3 h / Heating

2: 3.5 h / Heating

In benzene;
DOI:10.1007/BF00758818