N2-gamma-Glutamyl-p-hydrazinobenzoic acid

Base Information

Chemical Name:N2-gamma-Glutamyl-p-hydrazinobenzoic acid
CAS No.:69644-85-5
Molecular Formula:C₁₂H₁₅N₃O₅
Molecular Weight:281.268
Hs Code.:
DSSTox Substance ID:DTXSID4020660
Nikkaji Number:J1.006.369H
Wikidata:Q63088217
Mol file:69644-85-5.mol

Synonyms:N2-gamma-Glutamyl-p-hydrazinobenzoic acid;L-Glutamic acid, 5-(2-(4-carboxyphenyl)hydrazide);4-[2-(4-amino-4-carboxybutanoyl)hydrazino]benzoic acid;69644-85-5;BRN 5981372;N(sup 2)-(gamma-L-(+)-Glutamyl)-4-carboxyphenylhydrazine;Agaritinic acid;DTXSID4020660;LS-71795;N2-(g-Glutamyl)-4-carboxyphenylhydrazine;Q63088217

Suppliers and Price of N2-gamma-Glutamyl-p-hydrazinobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

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Chemical Property of N2-gamma-Glutamyl-p-hydrazinobenzoic acid

Chemical Property:

Refractive Index:1.5290 (estimate)
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：145.24000
Density:1.387g/cm³
LogP:1.63360
XLogP3:-2.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:281.10117059
Heavy Atom Count:20
Complexity:366

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)O)NNC(=O)CCC(C(=O)O)N
Isomeric SMILES:C1=CC(=CC=C1C(=O)O)NNC(=O)CC[C@@H](C(=O)O)N

Technology Process of N2-gamma-Glutamyl-p-hydrazinobenzoic acid

There total 4 articles about N2-gamma-Glutamyl-p-hydrazinobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-[N'-((S)-4-tert-Butoxycarbonylamino-4-carboxy-butyryl)-hydrazino]-benzoic acid

: 69644-85-5
[β-N-(γ-L(+)-glutamyl)-4-carboxyphenylhydrazine]

Guidance literature:: With trifluoroacetic acid; In various solvent(s); at 0 ℃; for 1h; Yield given;
DOI:10.1246/bcsj.54.2219

Reference yield:

: 619-67-0
4-Hydrazinobenzoic acid

: 69644-85-5
[β-N-(γ-L(+)-glutamyl)-4-carboxyphenylhydrazine]

Guidance literature:: Multi-step reaction with 3 steps

1: DCC, NEt₃ / CH₂Cl₂ / 3 h / Ambient temperature

2: 5percent Pd/C / ethanol; cyclohexene / 1 h / Heating

3: TFA / various solvent(s) / 1 h / 0 °C

With triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In ethanol; dichloromethane; cyclohexene;
DOI:10.1246/bcsj.54.2219

Reference yield:

: 30924-93-7
Boc-Glu-OBn

: 69644-85-5
[β-N-(γ-L(+)-glutamyl)-4-carboxyphenylhydrazine]

Guidance literature:: Multi-step reaction with 3 steps

1: DCC, NEt₃ / CH₂Cl₂ / 3 h / Ambient temperature

2: 5percent Pd/C / ethanol; cyclohexene / 1 h / Heating

3: TFA / various solvent(s) / 1 h / 0 °C

With triethylamine; dicyclohexyl-carbodiimide; trifluoroacetic acid; palladium on activated charcoal; In ethanol; dichloromethane; cyclohexene;
DOI:10.1246/bcsj.54.2219