6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine

Base Information

Chemical Name:6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine
CAS No.:95096-02-9
Molecular Formula:C₁₃H₁₀FN₅OS
Molecular Weight:303.32
Hs Code.:
DSSTox Substance ID:DTXSID60915121

Synonyms:95096-02-9;6-((4-FLUOROPHENYL)SULFINYL)PYRIDO[3,2-D]PYRIMIDINE-2,4-DIAMINE;6-((4-Fluorophenyl)sulfinyl)pyrido(3,2-d)pyrimidine-2,4-diamine;BRN 4526738;Pyrido(3,2-d)pyrimidine-2,4-diamine, 6-((4-fluorophenyl)sulfinyl)-;DTXSID60915121;6-(4-Fluorobenzene-1-sulfinyl)pyrido[3,2-d]pyrimidine-2,4(1H,3H)-diimine;6-(4-FLUOROBENZENESULFINYL)PYRIDO[3,2-D]PYRIMIDINE-2,4-DIAMINE

Suppliers and Price of 6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:2
Exact Mass:303.05900930
Heavy Atom Count:21
Complexity:393

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1F)S(=O)C2=NC3=C(C=C2)N=C(N=C3N)N

Technology Process of 6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine

There total 5 articles about 6-((4-Fluorophenyl)sulfinyl)pyrido[3,2-D]pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 371-42-6
4-Fluorothiophenol

: 95096-02-9
6-<(4-Fluorophenyl)sulfinyl>pyrido<3,2-d>pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / various solvent(s) / 1 h / 195 °C

2: 59 percent / Bromine complex of 1,4-diazabicyclo<2.2.2>octane / aq. acetic acid / 19 h / Ambient temperature

With Bromine complex of 1,4-diazabicyclo<2.2.2>octane; In acetic acid;
DOI:10.1002/jhet.5570210556

Reference yield:

: 16013-85-7,136901-10-5
2,6-dicholoro-3-nitropyridine

: 95096-02-9
6-<(4-Fluorophenyl)sulfinyl>pyrido<3,2-d>pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 5 steps

1: 58 percent / various solvent(s) / 0.25 h / 178 - 182 °C

2: 34 percent / conc.HCl, iron powder / methanol / 0.5 h / Heating

3: 57 percent / various solvent(s) / 0.17 h / 165 - 190 °C

4: 50 percent / various solvent(s) / 1 h / 195 °C

5: 59 percent / Bromine complex of 1,4-diazabicyclo<2.2.2>octane / aq. acetic acid / 19 h / Ambient temperature

With hydrogenchloride; Bromine complex of 1,4-diazabicyclo<2.2.2>octane; iron; In methanol; acetic acid;
DOI:10.1002/jhet.5570210556

Reference yield:

: 95095-84-4
3-amino-6-chloro-pyridine-2-carbonitrile

: 95096-02-9
6-<(4-Fluorophenyl)sulfinyl>pyrido<3,2-d>pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / various solvent(s) / 0.17 h / 165 - 190 °C

2: 50 percent / various solvent(s) / 1 h / 195 °C

3: 59 percent / Bromine complex of 1,4-diazabicyclo<2.2.2>octane / aq. acetic acid / 19 h / Ambient temperature

With Bromine complex of 1,4-diazabicyclo<2.2.2>octane; In acetic acid;
DOI:10.1002/jhet.5570210556