Technology Process of 2-hydroxy-1-(2,3,5-tri-O-acetylpentofuranosyl)pyridin-4(1H)-one
There total 5 articles about 2-hydroxy-1-(2,3,5-tri-O-acetylpentofuranosyl)pyridin-4(1H)-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
acetic acid;
for 5h;
under 760 Torr;
Ambient temperature;
DOI:10.1139/v81-498
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 71 percent / Br2
2: 82 percent / aniline, 47percent HBr / H2O / 4 h / 100 °C
3: chlorotrimethylsilane / 3 h / Heating
4: SnCl4 / 1,2-dichloro-ethane / 18 h / Ambient temperature
5: 80 percent / H2 / 5percent Pd/C / acetic acid / 5 h / 760 Torr / Ambient temperature
With
chloro-trimethyl-silane; hydrogen bromide; hydrogen; bromine; tin(IV) chloride; aniline;
palladium on activated charcoal;
In
water; acetic acid; 1,2-dichloro-ethane;
DOI:10.1139/v81-498
- Guidance literature:
-
Multi-step reaction with 3 steps
1: chlorotrimethylsilane / 3 h / Heating
2: SnCl4 / 1,2-dichloro-ethane / 18 h / Ambient temperature
3: 80 percent / H2 / 5percent Pd/C / acetic acid / 5 h / 760 Torr / Ambient temperature
With
chloro-trimethyl-silane; hydrogen; tin(IV) chloride;
palladium on activated charcoal;
In
acetic acid; 1,2-dichloro-ethane;
DOI:10.1139/v81-498