(-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride

Base Information

Chemical Name:(-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride
CAS No.:145511-51-9
Molecular Formula:C₁₅H₁₈N₂*ClH
Molecular Weight:262.782
Hs Code.:
DSSTox Substance ID:DTXSID70932627

Synonyms:145511-51-9;(-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride;1H-Pyrazino(3,2,1-jk)carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-, hydrochloride, (S)-;(5S)-12-methyl-1,4-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-9(16),10(15),11,13-tetraene;hydrochloride;DTXSID70932627;LS-127678;8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole--hydrogen chloride (1/1)

Suppliers and Price of (-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride

Chemical Property:

Vapor Pressure:2.39E-07mmHg at 25°C
Boiling Point:422.6°C at 760 mmHg
Flash Point:209.4°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:262.1236763
Heavy Atom Count:18
Complexity:303

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N3CCNC4C3=C2CCC4.Cl
Isomeric SMILES:CC1=CC2=C(C=C1)N3CCN[C@@H]4C3=C2CCC4.Cl

Technology Process of (-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride

There total 9 articles about (-)-8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-jk)carbazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 15932-34-0
5,6-dihydro-8-methyl-4H-pyrazino<3,2,1-j,k>carbazole hydrochloride

: 16154-78-2,145511-50-8,145511-51-9
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride

Guidance literature:: With sodium tetrahydroborate; 1.)15 deg C, 30 min 2.)80 deg C, 30 min;
DOI:10.1007/BF00505759

Reference yield: 68.4%

: 110951-52-5
(2-Chloro-ethyl)-(6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-amine

: 16154-78-2,145511-50-8,145511-51-9
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride

Guidance literature:: With sodium hydroxide; tetrabutylammomium bromide; In benzene; for 5h; Ambient temperature;
DOI:10.1007/BF00764890

Reference yield:

: 73166-21-9
8-Methyl-2,4,5,6-tetrahydro-1H-pyrazino[3,2,1-jk]carbazole; hydrochloride

: 16154-78-2,145511-50-8,145511-51-9
2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino(3,2,1-jk)carbazole monohydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: various solvent(s) / Heating

2: 75 percent / NaBH₄ / methanol; H₂O

3: H₂ / 10percent Pd/C

With sodium tetrahydroborate; hydrogen; palladium on activated charcoal; In methanol; water;
DOI:10.1002/hlca.19980810307