Oxonorfloxacin

Base Information

Chemical Name:Oxonorfloxacin
CAS No.:74011-42-0
Molecular Formula:C₁₆H₁₆FN₃O₄
Molecular Weight:333.319
Hs Code.:
DSSTox Substance ID:DTXSID10224816
Nikkaji Number:J142.438F
Wikidata:Q83103548
ChEMBL ID:CHEMBL735
Mol file:74011-42-0.mol

Synonyms:oxonorfloxacin

Suppliers and Price of Oxonorfloxacin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
4-Oxo Norfloxacin
1mg
$ 446.00

TRC
4-OxoNorfloxacin
1mg
$ 140.00

Medical Isotopes, Inc.
4-OxoNorfloxacin
1 mg
$ 640.00

American Custom Chemicals Corporation
4-OXO NORFLOXACIN 95.00%
5MG
$ 495.64

Total 4 raw suppliers

Chemical Property of Oxonorfloxacin

Chemical Property:

Vapor Pressure:5.19E-18mmHg at 25°C
Melting Point:316-319°C (dec.)
Boiling Point:654.3°C at 760 mmHg
Flash Point:349.5°C
PSA：91.64000
Density:1.424g/cm³
LogP:1.18870
Storage Temp.:Refrigerator
Solubility.:DMSO
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:333.11248416
Heavy Atom Count:24
Complexity:594

Purity/Quality:

95% ^*data from raw suppliers

4-Oxo Norfloxacin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNC(=O)C3)F)C(=O)O

Technology Process of Oxonorfloxacin

There total 5 articles about Oxonorfloxacin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 5625-67-2
2-Ketopiperazine

: 68077-26-9
7-chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

: 74011-42-0
Oxonorfloxacin

Guidance literature:: at 130 - 140 ℃; for 5h;
DOI:10.1021/jm00186a014

Reference yield:

: 367-21-5
3-chloro-4-fluorophenylamine

: 74011-42-0
Oxonorfloxacin

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / 2 h / 120 - 130 °C

2: diphenyl ether / 1 h / Heating

3: 90 percent / K₂CO₃ / dimethylformamide / 10 h / 80 - 90 °C

4: 90 percent / 2N NaOH / 2 h / Heating

5: 32 percent / 5 h / 130 - 140 °C

With sodium hydroxide; potassium carbonate; In diphenylether; N,N-dimethyl-formamide;
DOI:10.1021/jm00186a014

Reference yield:

: 70032-30-3
diethyl 2-[(3-chloro-4-fluorophenylamino)methylene]malonate

: 74011-42-0
Oxonorfloxacin

Guidance literature:: Multi-step reaction with 4 steps

1: diphenyl ether / 1 h / Heating

2: 90 percent / K₂CO₃ / dimethylformamide / 10 h / 80 - 90 °C

3: 90 percent / 2N NaOH / 2 h / Heating

4: 32 percent / 5 h / 130 - 140 °C

With sodium hydroxide; potassium carbonate; In diphenylether; N,N-dimethyl-formamide;
DOI:10.1021/jm00186a014