2-Amino-3-hydroxypropanehydrazide

Base Information

• Chemical Name: 2-Amino-3-hydroxypropanehydrazide
• CAS No.: 64616-76-8
• Molecular Formula: C₃H₉N₃O₂
• Molecular Weight: 119.123
• European Community (EC) Number: 613-642-7
• UNII: YHV5YH4C7H
• DSSTox Substance ID: DTXSID60866503
• Mol file: 64616-76-8.mol

Synonyms:2-amino-3-hydroxypropanehydrazide;DL-Serine hydrazide;64616-76-8;DL-Serine, hydrazide;YHV5YH4C7H;UNII-YHV5YH4C7H;RO 04-1419;2-Amino-3-hydroxypropanehydrazide (non-preferred name);SCHEMBL2208194;DTXSID60866503;AMY25339;AKOS006342010;SB46921;(2RS)-2-amino-3-hydroxypropanehydrazide;FT-0698754;EN300-251622

Chemical Property of 2-Amino-3-hydroxypropanehydrazide

Chemical Property:

• Vapor Pressure: 2.58E-11mmHg at 25°C
• Boiling Point: 482oC at 760 mmHg
• PKA: 12.11±0.10(Predicted)
• Flash Point: 245.3oC
• PSA: 104.86000
• Density: 1.334g/cm3
• LogP: -0.46320
• XLogP3: -2.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 119.069476538
• Heavy Atom Count: 8
• Complexity: 84.6

Purity/Quality:

99% ^*data from raw suppliers

Benserazide impurity A European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)NN)N)O

Technology Process of 2-Amino-3-hydroxypropanehydrazide

There total 1 articles about 2-Amino-3-hydroxypropanehydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyloxycarbonyl-DL-serine hydrazide (39978-41-1) → DL-serine hydrazide (64616-76-8)

Guidance literature:

With hydrogenchloride; hydrogen; platinum(IV) oxide;

Reference yield:

DL-serine hydrazide (64616-76-8) + benzaldehyde (100-52-7) → 2-Amino-3-hydroxy-propionic acid N'-benzyl-hydrazide (100227-22-3)

Guidance literature:

With hydrogen; platinum(IV) oxide; In water;

Reference yield:

DL-serine hydrazide (64616-76-8) + 1-phenyl-acetone (103-79-7,136675-26-8) → 2-Amino-3-hydroxy-propionic acid N'-(1-methyl-2-phenyl-ethyl)-hydrazide (60762-54-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In water;

upstream raw materials:

N-benzyloxycarbonyl-DL-serine hydrazide

Downstream raw materials:

2-Amino-3-hydroxy-propionic acid N'-benzyl-hydrazide

2-Amino-3-hydroxy-propionic acid N'-(1-methyl-2-phenyl-ethyl)-hydrazide

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