6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline

Base Information

Chemical Name:6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline
CAS No.:65222-36-8
Molecular Formula:C₁₆H₁₃N₃
Molecular Weight:247.299
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90215525
Nikkaji Number:J66.666A
Wikidata:Q83091569
Mol file:65222-36-8.mol

Synonyms:BR 1376;BR 76;BR-1376;BR-76

Suppliers and Price of 6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline

Chemical Property:

Boiling Point:524.8oC at 760 mmHg
Flash Point:249oC
PSA：41.57000
Density:1.307g/cm3
LogP:3.88110
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:247.110947427
Heavy Atom Count:19
Complexity:345

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C=CN=CC2=C(C3=C1NC4=C3C=NC=C4)C

Technology Process of 6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline

There total 8 articles about 6,11-Dimethyl-5H-pyrido(3',4':4,5)pyrrolo(2,3-g)isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 0.6%

: 73323-31-6
1-(1-chloro-5,8-dimethylisoquinolin-6-yl)-1H-v-triazolo<4,5-c>pyridine

: 73323-30-5
10-chloro-6,11-dimethyl-5H-pyrido<3',4':4,5>pyrrolo<2,3-g>isoquinoline

: 65222-36-8
5,11-Dimethyl-dipyrido<4,3-b><3,4-f>indol

Guidance literature:: In ethanol; triethylamine; for 87h; Irradiation;
DOI:10.1021/jo01299a028

Reference yield:

: 69022-60-2
1-(5,8-dimethyl-1-oxo-1,2-dihydroisoquinolin-6-yl)-1H-v-triazolo<4,5-c>pyridine

: 65222-36-8
5,11-Dimethyl-dipyrido<4,3-b><3,4-f>indol

Guidance literature:: Multi-step reaction with 2 steps

1: 84.6 percent / phosphorus oxychloride / 3 h / Heating

2: 2-methoxy-ethanol / 87 h / Irradiation

With trichlorophosphate; In 2-methoxy-ethanol;
DOI:10.1021/jo01299a028

Reference yield:

: 13091-23-1
4-chloro-3-nitropyridine

: 65222-36-8
5,11-Dimethyl-dipyrido<4,3-b><3,4-f>indol

Guidance literature:: Multi-step reaction with 4 steps

1: 62.3 percent / dimethylformamide / 360 h / Ambient temperature

2: 1) raney nickel/H₂, acetic acid, 2) NaNO₂/H₂O, 1.5h

3: 84.6 percent / phosphorus oxychloride / 3 h / Heating

4: 2-methoxy-ethanol / 87 h / Irradiation

With trichlorophosphate; In 2-methoxy-ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo01299a028