N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride

Base Information

Chemical Name:N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride
CAS No.:32414-28-1
Molecular Formula:C17H21Cl2NO
Molecular Weight:326.2607
Hs Code.:
DSSTox Substance ID:DTXSID20954177
NSC Number:11498

Synonyms:32414-28-1;SCHEMBL7276851;DTXSID20954177;FRHWGEORUKRDBY-UHFFFAOYSA-N;NSC11498;NSC-11498;N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride;N-Benzyl-2-chloro-N-(2-phenoxyethyl)ethan-1-amine--hydrogen chloride (1/1)

Suppliers and Price of N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride

Chemical Property:

Vapor Pressure:1.01E-05mmHg at 25°C
Boiling Point:371.7°C at 760 mmHg
Flash Point:178.6°C
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:325.1000197
Heavy Atom Count:21
Complexity:237

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN(CCOC2=CC=CC=C2)CCCl.Cl

Technology Process of N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride

There total 3 articles about N-(2-chloroethyl)-N-(2-phenoxyethyl)-N-benzylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 449195-24-8
2-[benzyl(2-phenoxyethyl)amino]-1-ethanol

: 32414-28-1
SKF 513 hydrochloride

Guidance literature:: 2-[benzyl(2-phenoxyethyl)amino]-1-ethanol; With hydrogenchloride; In benzene; at 0 ℃; for 0.25h;

With thionyl chloride; In benzene; for 8h; Heating;
DOI:10.1016/S0968-0896(01)00395-9

Reference yield:

: 55247-31-9
N-(2-Phenoxyethyl)benzylamine

: 32414-28-1
SKF 513 hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: 61 percent / K₂CO₃ / ethanol / 72 h / 110 °C

2.1: hydrogen chloride / benzene / 0.25 h / 0 °C

2.2: 22 percent / SOCl₂ / benzene / 8 h / Heating

With hydrogenchloride; potassium carbonate; In ethanol; benzene;
DOI:10.1016/S0968-0896(01)00395-9

Reference yield:

: 18861-15-9
N-benzyl-2-phenoxyacetamide

: 32414-28-1
SKF 513 hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: 50 percent / BH₃*SMe₂ / 1,2-dimethoxy-ethane / 16 h / 80 °C

2.1: 61 percent / K₂CO₃ / ethanol / 72 h / 110 °C

3.1: hydrogen chloride / benzene / 0.25 h / 0 °C

3.2: 22 percent / SOCl₂ / benzene / 8 h / Heating

With hydrogenchloride; dimethylsulfide borane complex; potassium carbonate; In 1,2-dimethoxyethane; ethanol; benzene;
DOI:10.1016/S0968-0896(01)00395-9