DL-beta-Hydroxybutyric acid sodium salt, ~98%

Base Information

• Chemical Name: DL-beta-Hydroxybutyric acid sodium salt, ~98%
• CAS No.: 150-83-4
• Molecular Formula: C4H8 O3 . Na
• Molecular Weight: 126.088
• Hs Code.: 29181990
• Mol file: 150-83-4.mol

Synonyms:SCHEMBL1061280;DL-beta-Hydroxybutyric acid sodium salt, ~98%;Butanoic acid, 3-hydroxy-, sodium salt (1:1);(+/-)-Sodium 3-hydroxybutyrate, >=99.0% (NT)

Chemical Property of DL-beta-Hydroxybutyric acid sodium salt, ~98%

Chemical Property:

• Vapor Pressure: 0.000979mmHg at 25°C
• Melting Point: 167-170 °C
• Boiling Point: 269.2°Cat760mmHg
• Flash Point: 121°C
• PSA: 60.36000
• Density: g/cm³
• LogP: -1.49280
• Storage Temp.: 2-8°C
• Sensitive.: Hygroscopic
• Solubility.: Methanol (Slightly, Sonicated), Water (Slightly)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 127.03711339
• Heavy Atom Count: 8
• Complexity: 69.3

Purity/Quality:

98% ^*data from raw suppliers

DL-3-Hydroxybutyric Acid, Sodium Salt ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(CC(=O)O)O.[Na]
• Uses: Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems. (±)-Sodium 3-hydroxybutyrate has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid ?-oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate).
• Biological Functions: Neuroprotective compound in experimental models of neurodegenerative diseases. Shown to be oxidized as an energetic substrate in the brain during starvation. May inhibit brain glucose oxidation, which may account for the suppression of hepatic glucose production observed after administration of ketone bodies in humans.

Technology Process of DL-beta-Hydroxybutyric acid sodium salt, ~98%

There total 1 articles about DL-beta-Hydroxybutyric acid sodium salt, ~98% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1.3-butanediol (18826-95-4,107-88-0) → sodium DL-3-hydroxybutyrate (150-83-4)

Guidance literature:

With sodium hydroxide; Rh(trop2NH)(PPh₃)(OTf); water; cyclohexanone; at 25 ℃; for 12h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/anie.200804757

Reference yield: 88.0%

benzyl bromide (100-39-0) + sodium DL-3-hydroxybutyrate (150-83-4) → benzyl 3-hydroxybutyrate (1135-39-3)

Guidance literature:

In acetonitrile; for 48h; Heating;

DOI:10.1021/js980065o

Reference yield:

sodium DL-3-hydroxybutyrate (150-83-4) → 3-Hydroxybutyric acid (300-85-6,625-71-8,26063-00-3,29435-48-1)

Guidance literature:

With hydrogenchloride; In water; pH=2;

upstream raw materials:

1.3-butanediol

Downstream raw materials:

benzyl 3-hydroxybutyrate

3-Hydroxybutyric acid

Refernces