2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-

Base Information

Chemical Name:2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-
CAS No.:81638-99-5
Molecular Formula:C₁₄H₂₁N₃O₂
Molecular Weight:263.34
Hs Code.:
DSSTox Substance ID:DTXSID901002105
Wikidata:Q76156478

Synonyms:2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-;(S)-5-Oxo-N-(4-(1-piperidinyl)-2-butynyl)-2-pyrrolidinecarboxamide;81638-99-5;DTXSID901002105;LS-137418;5-Hydroxy-N-[4-(piperidin-1-yl)but-2-yn-1-yl]-3,4-dihydro-2H-pyrrole-2-carboximidic acid

Suppliers and Price of 2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-

Chemical Property:

Vapor Pressure:9.01E-13mmHg at 25°C
Boiling Point:564.6°Cat760mmHg
Flash Point:295.3°C
Density:1.156g/cm³
XLogP3:-0.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:263.16337692
Heavy Atom Count:19
Complexity:401

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)CC#CCNC(=O)C2CCC(=O)N2
Isomeric SMILES:C1CCN(CC1)CC#CCNC(=O)[C@@H]2CCC(=O)N2

Technology Process of 2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)-

There total 2 articles about 2-Pyrrolidinecarboxamide, 5-oxo-N-(4-(1-piperidinyl)-2-butynyl)-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 57061-80-0
4-piperidin-1-yl-but-2-ynylamine

: 28990-85-4
pentachlorophenyl ester of L-pyroglutamic acid

: 81638-99-5
(S)-5-Oxo-pyrrolidine-2-carboxylic acid (4-piperidin-1-yl-but-2-ynyl)-amide

Guidance literature:: In N,N-dimethyl-formamide; for 16h; Ambient temperature;

Reference yield:

: 7314-22-9
N-(4-(piperidino-1-yl)but-2-yn-1-yl)isoindoline-1,3-dione

: 81638-99-5
(S)-5-Oxo-pyrrolidine-2-carboxylic acid (4-piperidin-1-yl-but-2-ynyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / hydrazine hydrate / ethanol / 1.5 h / Heating

2: 60 percent / dimethylformamide / 16 h / Ambient temperature

With hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;