2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide

Base Information

• Chemical Name: 2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide
• CAS No.: 84012-61-3
• Molecular Formula: C11H13 Cl2 N O
• Molecular Weight: 246.136
• Hs Code.: 2924299090
• European Community (EC) Number: 281-702-6
• DSSTox Substance ID: DTXSID60232901
• Nikkaji Number: J332.957G
• Wikidata: Q83114098
• Mol file: 84012-61-3.mol

Synonyms:84012-61-3;EINECS 281-702-6;2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide;2-chloro-N-(4-chlorophenyl)-N-(propan-2-yl)acetamide;2-chloro-N-(4-chlorophenyl)-N-isopropylacetamide;SCHEMBL22311444;DTXSID60232901;Z1562153657

Chemical Property of 2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide

Chemical Property:

• Vapor Pressure: 0.000107mmHg at 25°C
• Boiling Point: 337.2°C at 760 mmHg
• Flash Point: 157.7°C
• PSA: 20.31000
• Density: 1.244g/cm³
• LogP: 3.32020
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 245.0374194
• Heavy Atom Count: 15
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N(C1=CC=C(C=C1)Cl)C(=O)CCl

Technology Process of 2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide

There total 2 articles about 2-Chloro-N-(4-chlorophenyl)-N-(1-methylethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-(4-chlorophenyl)-N-isopropylamine (770-40-1) + chloroacetyl chloride (79-04-9) → 4-chlorophenyl-N-isopropyl-α-chloroacetanilide (84012-61-3)

Guidance literature:

With triethylamine; In benzene; for 2h; Heating;

Reference yield:

4-chloro-aniline (106-47-8) → 4-chlorophenyl-N-isopropyl-α-chloroacetanilide (84012-61-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / Et₃N / benzene / 5 h / Heating

2: 90 percent / Et₃N / benzene / 2 h / Heating

With triethylamine; In benzene;

Reference yield: 87.0%

4-chlorophenyl-N-isopropyl-α-chloroacetanilide (84012-61-3) → 2-amino-N-(4-chlorophenyl)-N-isopropylacetamide

Guidance literature:

With ammonia; In methanol; at 50 ℃;

upstream raw materials:

N-(4-chlorophenyl)-N-isopropylamine

chloroacetyl chloride

4-chloro-aniline

Downstream raw materials:

Dithiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-diethyl ester

anilofos

Dithiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-dipropyl ester

Thiophosphoric acid S-{[(4-chloro-phenyl)-isopropyl-carbamoyl]-methyl} ester O,O'-diethyl ester