Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate

Base Information

Chemical Name:Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate
CAS No.:64989-75-9
Molecular Formula:C18H15FN2O2
Molecular Weight:310.328
Hs Code.:
DSSTox Substance ID:DTXSID701187818

Synonyms:SCHEMBL11768308;DTXSID701187818;Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate;64989-75-9

Suppliers and Price of Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:310.11175589
Heavy Atom Count:23
Complexity:401

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=NN(C=C1C2=CC=CC=C2)C3=CC=CC=C3F

Technology Process of Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate

There total 4 articles about Ethyl 1-(2-fluorophenyl)-4-phenyl-1H-pyrazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(2-Fluoro-phenyl)-5-morpholin-4-yl-4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester

: 64989-75-9
1-(2-fluoro-phenyl)-4-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 100 ℃; for 1h;

Reference yield:

: 39166-25-1
(E)-N-(2-phenylethenyl)morpholine

: 64989-75-9
1-(2-fluoro-phenyl)-4-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 1.) 3h, reflux, 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; chloroform; water;

Reference yield:

: 64989-74-8
[(2-fluorophenyl)hydrazono]chloroacetic acid ethyl ester

: 64989-75-9
1-(2-fluoro-phenyl)-4-phenyl-1H-pyrazole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / CHCl₃ / 1.) 3h, reflux, 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; chloroform; water;